Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05215223

Acronym

WBV

Enrollment

Registered

2022-01-31

Start date

2022-03-30

Completion date

2023-10-10

Last updated

2023-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin Resistance, Polycystic Ovarian Syndrome

Brief summary

The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome

Detailed description

polycystic ovarian syndrome is a complex endocrine condition characterized by metabolic abnormalities such as insulin resistance, excess weight or obesity, diabetes, and an increased risk of cardiovascular disease.Despite previous studies reported that physical exercise improves insulin resistance in females with polycystic ovarian syndrome, there is no study yet investigate the effect of whole body vibration on insulin resistance

Interventions

DEVICEwhole body vibration

the patients will stand on whole body vibration device with maintaining squatting position while keeping their trunk extended. The first training session will be consisted of three sets of 1 min and will be separated by a 1-min of standing rest. intensity will 1 mm. Then one set will be added every session

DEVICETreadmill

Females will be asked to perform moderate intensity aerobic exercise for 45 minutes for 3 times per week for 8 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 35 Years

Healthy volunteers

Inclusion criteria

1. Females with polycystic ovarian syndrome. 2. Their ages will range from 20 to 35 years.

Exclusion criteria

* 1-Smoking. 2-History of chronic disease.

Design outcomes

Primary

Measure	Time frame	Description
Homeostasis Model Assessment (HOMA-IR)	eight weeks	Estimate insulin resistance (IR), it will be calculated according to the formula: fasting insulin (microU/L) x fasting glucose (nmol/L)/22.5.

Secondary

Measure	Time frame	Description
Waist circumference	eight weeks	by a tape measurement around the waist
waist hip ratio	eight weeks	The formula = waist circumference / hip circumference.
LH/FSH ratio	Eight weeks	To assess the severity of PCOS

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026