Psychiatric Illness
Conditions
Brief summary
Adults hospitalized in psychiatry have an increased frequency of somatic disorders, in particular various liver diseases (viral hepatitis, non-alcohol related liver steatosis, alcohol related liver disease). The evaluation of these liver disorders in psychiatric inpatients remains very little explored in France, contributing to the poor overall medical status of psychiatric patients. The LIVERSPIN study aims to estimate the prevalence rates of liver pathologies in psychiatric inpatients and to explore the factors associated with the existence of a liver pathology
Detailed description
The LIVERSPIN study aims to estimate the prevalence rates of liver disease in psychiatric inpatients and to explore factors associated with the existence of liver disease. All hospitalized patients can potentially be recruited. They will benefit from the usual clinical and paraclinical examinations as part of their hospitalization diagnostic work-up. For the determination of biological analyses, a blood sample will be taken following inclusion as well as a Fibroscan examination.
Interventions
DIAGNOSTIC_TESTTo estimate the prevalence rates of liver disease in psychiatric inpatients and to explore factors associated with the existence of liver disease.
Patients will receive the usual clinical and paraclinical examinations as part of their hospitalization diagnostic workup. For the biological analyses, a blood sample will be taken following inclusion as well as a Fibroscan examination. Data will be collected from the patient, or if necessary from the health care team, using the medical record (interview and/or self-questionnaires).
Sponsors
Hospices Civils de Lyon
Hôpital le Vinatier
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Monocentric, non randomized, non comparative cross-sectional study
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>18 years old * Social insurance * Current hospitalization in any psychiatric unit of the participating center * Adult or legal representative who has given written and informed consent to participate in the study. By default, the oral consent of the adult will be obtained (as well as the written consent of the legal representative) * Information given to the curator(for people under curatorship)
Exclusion criteria
* \- Clinical state of the patient which do not allow the collection of study data (according to the investigator)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HCV diagnosis | At inclusion | HCV diagnosis defined by positive HCV antibodies in blood |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| HBV diagnosis | At inclusion | HBV diagnosis defined by positive HBsAg in blood |
| HIV diagnosis | At inclusion | HIV diagnosis defined by positive anti-HIV1 or anti-HIV2 antibodies in blood |
| Suspicion of NAFLD | At inclusion | Suspicion of NAFLD on FIB-4 and the interrogation |
| Suspicion of alcoholic liver disease | At inclusion | Suspicion of alcoholic liver disease on FIB-4 and the interrogation |
Countries
France
Outcome results
None listed