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Blood Donation and Subjective Well-being

The Relationship Between Blood Donation and Subjective Well-being

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05213130
Enrollment
601
Registered
2022-01-28
Start date
2022-01-18
Completion date
2022-03-16
Last updated
2026-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Donation, Happiness

Brief summary

This study investigates the psychological effects of blood donation among adult donors at the Guangzhou Blood Center. The primary objective is to examine whether a brief gratitude-based intervention delivered after donation enhances donors' subjective well-being (SWB) and basic psychological need (BPN) satisfaction. Participants who complete a whole-blood donation are randomly assigned to either an Intervention group, receiving a standardized gratitude reinforcement message accompanied by a vignette emphasizing the life-saving impact of donation, or a Control group that receives no additional message. All participants complete questionnaires at Time 1 (immediately after donation) and at Time 2 (4-22 days later), assessing SWB and related psychosocial variables.

Interventions

OTHERInformation

A reminder to inform donors that their blood has saved patient's life in a questionnaire.

Sponsors

Guangzhou Blood Center
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Successfully completed a whole-blood donation at the Guangzhou Blood Center during the study period. * Able to read and understand the study materials and provide informed consent. * Provided the correct answer to a control question in the questionnaire * Provided their phone number. * Donated blood was successfully supplied to the hospitals.

Exclusion criteria

* Whole blood donors with positive or suspicious serological results.

Design outcomes

Primary

MeasureTime frameDescription
Score of Subjective Well-Being at Time 24-22 days after donationSubjective well-being (SWB) is assessed at follow-up using a validated multi-item measure capturing life satisfaction and affective well-being. Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them. Scores range from low to high levels of well-being. The primary objective is to evaluate whether exposure to the gratitude-based intervention leads to higher SWB relative to the control condition.

Secondary

MeasureTime frameDescription
Score of Basic Psychological Needs Satisfaction at Time 1Immediately after donationBaseline basic psychological needs (BPN) satisfaction is measured using a 9-item Basic Psychological Needs Scale (validated Chinese version). The scale contains subscales for autonomy, competence, and relatedness, using a 7-point scale ranging from 1 (not at all true) to 7 (very much true). Each of the three subscales was averaged to form an index of general BPN satisfaction. This measure captures donors' immediate psychological experience following donation. Higher scores indicate greater psychological need satisfaction.
Score of Basic Psychological Needs Satisfaction at Time 24-22 days after donationThe same basic psychological needs satisfaction (BPN) scale is administered at follow-up to examine changes after the intervention. It is measured using a 9-item Basic Psychological Needs Scale (validated Chinese version). The scale contains subscales for autonomy, competence, and relatedness, using a 7-point scale ranging from 1 (not at all true) to 7 (very much true). Each of the three subscales was averaged to form an index of general BPN satisfaction. Higher scores indicate greater psychological need satisfaction.
Score of Subjective Well-being at Time 1Immediately after donationBaseline Subjective well-being (SWB) is measured using a validated multi-item measure capturing life satisfaction and affective well-being. Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them. Scores range from low to high levels of well-being.
Score of Blood Donation Intention Score at Time 24-22 days after donationIntention to donate blood again in the future at Time 2 is measured using a single self-report intention item rated from 1 (very unlikely) to 7 (very likely), with higher scores indicating stronger intention to donate. The same item is administered at Time 1 and Time 2 to assess changes over time and to examine potential effects of the intervention on future donation motivation.
Re-Donation Rate within One YearUp to 12 months after the initial donationActual re-donation rate is obtained from the Guangzhou Blood Centre's donation records. The variable indicates whether the participant returned for another whole-blood or component donation within one year.
Score of Blood Donation Intention at Time 1Immediately after donationIntention to donate blood again in the future at Time 1 is measured using a single self-report intention item rated from 1 (very unlikely) to 7 (very likely), with higher scores indicating stronger intention to donate. The same item is administered at Time 1 and Time 2 to assess changes over time and to examine potential effects of the intervention on future donation motivation.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 29, 2026