Effects of Topical Cream for Pain Relief

Document Magnitude and Timing for Pain Relief of Topical Cream

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05213052

Enrollment

Registered

2022-01-28

Start date

2021-08-01

Completion date

2022-05-01

Last updated

2022-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain

Brief summary

To perform a clinical proof-of-concept study on a novel topical formula for pain relief.

Detailed description

An open-label study where each participant will be involved in the study for 4 weeks. During the study participants will use the topical cream 1-2 times daily on the anatomical area(s) causing the most pain.

Interventions

OTHERTopical cream

Topical cream applied to painful joint or muscle

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Intervention model description

An open-label study design where all study participants will receive the active test product and no placebo is used.

Eligibility

Sex/Gender

ALL

Age

21 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI between 18.5 and 34.9 kg/m2 (inclusive) * Chronic joint/muscle related pain for at least past 6 months * Experiencing chronic pain in at least one specific anatomical area for more than 6 months.

Exclusion criteria

* Cancer during past 12 months * Chemotherapy during past 12 months * Currently taking prescription pain medications * Getting regular joint injections (such as cortisone shots); * Immunization during last month * Participation in another clinical trial study during this trial, involving an investigational product or lifestyle change * Regularly experiencing headaches, including migraines * Serious active illness within past 6 months * Significant active uncontrolled illness (such as lymphoma, liver disease, kidney failure, heart failure). * Skin allergies related to ingredients in test product.

Design outcomes

Primary

Measure	Time frame	Description
Change in degree of pain	4 weeks	Pain questionnaire - yes/no, score 0-24 hours

Secondary

Measure	Time frame	Description
Activity level	4 weeks	Activities of daily living questionnaire

Other

Measure	Time frame	Description
Wellness	4 weeks	Wellness questionnaire - Score 0-10 \[0 being strongly disagree, 10 being strongly agree\]

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026