Total Hip Arthroplasty
Conditions
Brief summary
Nielsen et al. reported that when iliopsoas plane block was performed on healthy volunteers, the injection solution in Hip MRI was confined to the myofascial compartment, which was known to include all sensory branches of the femoral nerve that control the hip joint. The maximal muscle strength of knee extension did not decrease before and after Iliopsoas plane block in Volunteer. Since there is no clinical study conducted on patients after the volunteer study, the investigators intend to evaluate the analgesic and motor preserving effects of the iliopsoas plane block in a group of patients undergoing total hip arthroplasty.
Interventions
PROCEDUREiliopsoas plane block group
Ultrasound-guided iliopsoas plane block with 0.75% ropivacaine 10 ml and epinephrine 0.05 ml (1:200,000) 10 ml
PROCEDUREsham block group
Ultrasound-guided iliopsoas plane block with normal saline 10 ml
Sponsors
Gangnam Severance Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Double
Intervention model description
Parallel assignment
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients 19 years of age or older who are expected to undergo unilateral hip arthroplasty 2. ASA PS 1-3
Exclusion criteria
1. Revision total hip arthroplasty 2. Allergy to drugs used in the study 3. Patients with moderate or more hepatic impairment (AST/ALT is more than 2.5 times the upper limit of normal) 4. Estimated glomerular filtration rate \< 30 mL/min/1.73m2 5. Opioid dependence 6. Prolongation of PT and aPTT more than twice the upper limit of normal 7. Pre-existing neurological or anatomical disorders of the lower extremities 8. Serious psychiatric disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Numeric rating scale pain score at rest | up to 48 hours after the surgery | Pain intensity at rest will be evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) 1, 6, 24, and 48 hours after the surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numeric rating scale pain score at movement | up to 48 hours postoperatively | Pain intensity during 45-degree passive flexion of the hip with the ipsilateral knee flexed naturally will be evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) 1, 6, 24, and 48 hours after the surgery. |
| Postoperative opioid consumption | postoperative 24, 48hours | morphine equivalent dose |
Countries
South Korea
Outcome results
None listed