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TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection

Comparison Between Thoracic Epidural Anaesthesia, Erector Spinae Block and Paravertebral Block During Single-lung Ventilation for Lung Resection in Lateral Decubitus Position: A Prospective Randomized Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05211791
Enrollment
90
Registered
2022-01-27
Start date
2022-01-10
Completion date
2023-10-20
Last updated
2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Diseases, Pain, Acute

Brief summary

Thoracotomy operations are known to be painful surgical procedures, so providing effective intraoperative and postoperative analgesia is so important for all anaesthesiologists. Ineffective pain management interferes with deep breathing, coughing, and remobilization resulting in atelectasis and pneumonia. Ultrasound-guided ESP block is a myofascial plane block that provides analgesia for thoracic or abdominal segmental innervation depending on the level of the injection site. Thoracic epidural analgesia (TEA) is considered the gold standard analgesic technique for thoracic surgeries. But the invasiveness of this technique, the rare but serious neurologic complications and the failure rates up to 30% are the disadvantages of epidural analgesia

Detailed description

The aim of this study is to compare the effect of different blocks as TEA, erector spinae block or paravertebral block on improving peri-operative analgesia and post-operative outcome in pulmonary resection in adult patients.

Interventions

PROCEDUREerector spinae block

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

PROCEDUREparavertebral block anesthesia

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

insertion of Thoracic epidural catheter for anesthesia analgesia at level of T6

Sponsors

South Egypt Cancer Institute
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* aged between 18 to 70 years old for elective lung resection. with American Society of Anesthesiology physical status (ASA-PS) I-III

Exclusion criteria

* Total pneumonectomy * Hepatic or renal dysfunction. * contraindications for epidural anesthesia as Coagulopathy and neurological and spinal deficits. * emergency cases

Design outcomes

Primary

MeasureTime frameDescription
peri-operative analgesiaup to 48 hours postoperativeVisual Analogue score (resting and during cough) from 0 (no pain) to 10 (worst pain pain measurement

Countries

Egypt

Contacts

Primary ContactAlaa A Elzohry, MD
alaa.zohiry@hotmail.com+201007356462

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026