Coronary Artery Disease Severity in Newly Diagnosed Dysglycemia

Severity of Newly Diagnosed Coronary Artery Disease in Patients With Newly Diagnosed Diabetes and Pre-diabetes: A Cohort Study in a Cardiac Center in Saudi Arabia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05210972

Enrollment

150

Registered

2022-01-27

Start date

2021-07-01

Completion date

2022-09-30

Last updated

2022-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease, Dysglycemia

Brief summary

This cohort study will measure how severe is the coronary artery disease (CAD), at time of CAD diagnosis, clinically and angiographically in the different cohorts of newly diagnosed diabetes and prediabetes versus normal glycemia patients in the study center.

Interventions

RADIATIONCardiac catheterization

All the study population will be exposed to diagnostic coronary angiography and invasive coronary intervention as per standard guidelines.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All adult patients with consents. * First time diagnosis of CAD and no prior diagnosis of diabetes milletus (DM), or prediabetes. * Coronary artery disease confirmed by invasive coronary angiography.

Exclusion criteria

1. Patients with known significant anemia, increased hemoglobin turnover, active hemoglobin drops or on erythropoietin therapy. 2. Pregnant and post-partum patients (up to 3 months post-delivery). 3. Patients with severe chronic renal failure (estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.72 m2). 4. Patients on any medications with glucose lowering effects.

Design outcomes

Primary

Measure	Time frame	Description
Coronary artery disease severity	1 day (During the hospital admission)	To measure how severe is the CAD, at time of CAD diagnosis, clinically and angiographically in the different cohorts of newly diagnosed diabetes and prediabetes versus normal glycemia patients.

Secondary

Measure	Time frame	Description
Correlation of HbA1c to CAD severity	1 day (During the hospital admission)	To correlate the level of HbA1c to the clinical and angiographic severity of CAD in the study populations

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026