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Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery

Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05210556
Enrollment
778
Registered
2022-01-27
Start date
2021-12-22
Completion date
2024-06-30
Last updated
2025-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic Cancer, Surgical Complication, Surgical Site Infection

Keywords

surgical site infection, gynecologic cancer

Brief summary

The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.

Detailed description

This is a retrospective chart review study. Patients who underwent scheduled intra-abdominal surgery with a WellSpan gynecologic oncologist will be identified and their chart reviewed for demographic data of age, race, BMI, comorbidities, and type of surgery. Those patients who had a deep organ/space surgical site infection within 30 days postoperatively will be identified. The numbers of these infections before and after August 2020, at which time all patients moving forwards were prescribed antibiotic bowel preparation, will then be statistically analyzed and compared to see if the institution of the antibiotic bowel preparation was associated with a reduction in surgical site infection.

Interventions

OTHERDiagnosed with Surgical Site Infection

As an observational study, this notates patients who were diagnosed with a deep organ/space surgical site infection within 30 days of surgery

Sponsors

WellSpan Health
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 99 Years
Healthy volunteers
Yes

Inclusion criteria

\- Underwent scheduled intra-abdominal surgery with a WellSpan gynecologic oncologist

Exclusion criteria

* Unscheduled surgery * Intraoperative consult by a WellSpan gynecologic oncologist

Design outcomes

Primary

MeasureTime frameDescription
Surgical Site Infection Rates Associated with Antibiotic Bowel Prep2019-2021Rate of surgical site infection rate as associated with or without use of antibiotic bowel preparation

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026