Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
Conditions
Brief summary
Critical limb threatening ischemia CLTI 'is not a separate local disease but also it is a part of generalized vascular disorder. A clinical syndrome that can be presented by many symptoms and signs as rest pain, gangrene and chronic ulceration more than 2 weeks (1).
Detailed description
The Global Vascular guidelines 'GVG proposes a new Global Anatomic Staging System (GLASS), GLASS incorporates two novel and important concepts, the target arterial path (TAP) and estimated limb-based patency (LBP). Based on appropriate angiographic imaging, the TAP is defined by the treating surgeon or internationalist as the optimal arterial pathway to restore in-line (pulsatile) flow to the ankle and foot. LBP allows more direct comparison of anatomic outcomes across revascularization strategies in CLTI. The complexity of disease traversed by the TAP is integrated in the GLASS. Femoropopliteal (FP) and infrapopliteal (IP) arterial segments are individually graded on a scale of 0 to 4.(2)(3) Using a consensus based matrix, these segmental grades are combined into three overall GLASS (I-III) stages for the limb, reflecting the complexity of the disease with a proposed likelihood of immediate technical failure ' ITF and 1 year LBP after endovascular intervention of TAP ' (1)
Interventions
None listed
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with infrainguinal CLTI
Exclusion criteria
* Patients with concomitant Aorto-iliac lesions * Acute ischemia patients * Post Traumatic ischemia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Imitate technical failure | 1 year | Failure of passage of wire or Recoil of vessels during angioplasty |
| Limb based patency at 1 year | 1 year | Patent vessels after endovascular management |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Amputation free survival at 1 year | 1 year | Limb preserved after endovascular intervention |
| Mortality Rate at 1 year | 1 year | Death after endovascular intervention |
| Amputation rate at 1 year | 1 year | Amputation after endovascular intervention |
Countries
Egypt
Contacts
Primary ContactHaitham Ali Hassan, MD
Backup ContactAyman Elsayed Hassaballah, MD
Outcome results
None listed