Cryptosporidiosis
Conditions
Brief summary
Cryptosporidium species are increasingly recognized as important enteric pathogens that infect a broad range of hosts including human, domestic and wild animals worldwide, causing asymptomatic or mild-to-severe gastrointestinal disease in their host species. There are 38 species of Cryptosporidium that have been described, going from amphibian parasites to mammals ones, with over 40 genotypes infecting mammals, although Cryptosporidium parvum and Cryptosporidium hominis are the two species predominantly reported in human infections. In Cairo and Sharkyia governorates in Egypt, Cryptosporidium is a common intestinal parasite among children, especially in diarrheic, preschool-aged children, with a predominance of C. hominis indicates anthroponotic rather than zoonotic transmission. Also in the sohag governorate, Cryptosporidium infection is a common intestinal parasite, as in the last five years its prevalence about 35% but there is no study clarify predominant genotype of Cryptosporidium in sohag.
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
1. Age: any age 2. Sex: male -female 3. Residence: rural-urban 4. Animal contact. 5. Immune status: immunocompetent - immunocompromised 6. Clinical manifestations: diarrhea -abdominal pain- fever- vomiting.
Exclusion criteria
* patients taking treatment for cryptosporidiosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| estimate the prevalence and clarify the species and genotypes/subtypes of Cryptosporidium spp. in sohag. | 24 weeks |
Secondary
| Measure | Time frame |
|---|---|
| clarify the relationship of them in a phylogenetic context and to provide additional information on the molecular epidemiology of this parasite in our locality | 24 weeks |
| clarify the predominant clinical manifestation of each genotypes/subtypes of Cryptosporidium spp | 24 weeks |
| clarify the relationship between genotypes/subtypes of Cryptosporidium spp. and different risk factors. | 24 weeks |
Countries
Egypt
Contacts
Primary ContactSalwa GA Omran, assistant lecturer
Outcome results
None listed