Congenital Cataract Polar Posterior
Conditions
Keywords
visual function, posterior polar cataracts, posterior lenticonus
Brief summary
Prognostic factors determining visual outcomes in patients with posterior polar cataracts and posterior lenticonus are largely unknown. In this trial, the investigators aimed to evaluate the visual outcomes in patients with posterior polar cataracts and posterior lenticonus and try to find out the factors associated with the visual acuity after surgery. Patients enrolled in this study will be followed for at least 6 months and will have study visits at 1 day, 1 week, 1 month, 3 month, 6 month postoperatively.
Detailed description
Congenital cataract patients have a wide range of presentations of lens opacities with different impact on visual function. Polar cataracts are opacities of the subcapsular cortex in the polar regions of the lens. To our knowledge, anterior polar cataracts are usually visually insignificant, however, even a small posterior lens opacity can impair vision because of their close proximity to the macula. Visual impairment could be caused by an opacity that blocks the visual axis, refractive error, posterior lesion-induced optical distortion, or amblyopia. Therefore, surgery is often recommended when visual function is significantly affected. The primary indication for surgical intervention in cataract is poor visual acuity. However, the previous studies have shown that preoperative visual acuity is a poor predictor of improvement in the subjectively experienced quality of vision after cataract surgery. Considering the increased risk for capsule rupture during surgery and the sacrifice of accommodation after cataract surgery in eyes with posterior lens opacities, the decision of surgical intervention must be carefully weighed. In this trial, the investigators aimed to evaluate the changes of visual function, including visual acuity, modulation transfer function, ocular aberrations in the participants with posterior lens opacities. Moreover, various factors which might be associated with postoperative visual acuity were explored. The participants enrolled in this study will be followed for at least 6 months and will have study visits at 1 day, 1 week, 1 month, 3 month, 6 month postoperatively.
Interventions
PROCEDUREPhacomulsification lens removal cataract surgery with Intraocular lens(IOL) implantation
Phacomulsification lens removal cataract surgery with IOL implantation in both two groups
Sponsors
Sun Yat-sen University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
3 Years to 14 Years
Inclusion criteria
* Children with posterior polar cataracts or posterior lenticonus who need cataract surgery * Aged 3-14 years * Have signed a consent form * Can be followed
Exclusion criteria
* Have relevant ocular disease other than congenital cataract * Could not cooperate to the examinations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity (BCVA) | 6 month after surgery | Visual acuity (BCVA) measured by ETDRS chart after surgery |
| Stereoacuity | 6 month after surgery | Stereoacuity measured at 40 cm using the Randot stereotests |
| modulation transfer function (MTF) | 6 month after surgery | MTF measured with the Optical Quality Analysis System |
| monochromatic aberrations | 6 month after surgery | monochromatic aberrations measured by the iTrace Dynamic Laser Refraction |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| modulation transfer function (MTF) | before surgery | MTF measured with the Optical Quality Analysis System |
| Location of the cataracts | before surgery | divided into central, paracentral, and peripheral |
| monochromatic aberrations | before surgery | monochromatic aberrations measured by the iTrace Dynamic Laser Refraction system |
| size of lens lesion | before surgery | measured by image J |
| Visual acuity (BCVA) | before surgery | Visual acuity (BCVA) measured by ETDRS chart before surgery |
| Stereoacuity | before surgery | Stereoacuity measured at 40 cm using the Randot stereotests |
Countries
China
Outcome results
None listed