Muscle Atrophy
Conditions
Brief summary
Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.
Detailed description
Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.
Interventions
DIETARY_SUPPLEMENTWhole egg powder
Nutritional supplementation during a 12 week resistance training program
DIETARY_SUPPLEMENTWhey protein powder
Nutritional supplementation during a 12 week resistance training program
DIETARY_SUPPLEMENTMaltodextrin placebo
Nutritional supplementation during a 12 week resistance training program
Sponsors
Egg Farmers of Canada
University of Saskatchewan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Resistance training experience for at least one year
Exclusion criteria
* Having taken any nutritional supplements the past 30 days * Currently using anabolic steroids * Currently taking corticosteroids * Allergies to dairy or egg products * Identifying any medical conditions as determined by the Get Active Questionnaire
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in lean tissue mass | 12 weeks | Lean tissue mass measured by DXA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in biceps muscle thickness | 12 weeks | biceps muscle thickness measured by ultrasound |
| Change in triceps muscle thickness | 12 weeks | triceps muscle thickness measured by ultrasound |
| Change in quadriceps muscle thickness | 12 weeks | quadriceps muscle thickness measured by ultrasound |
| Change in hamstrings muscle thickness | 12 weeks | hamstrings muscle thickness measured by ultrasound |
| Change in fat mass | 12 weeks | Fat mass measured by DXA |
| Change in leg squat strength | 12 weeks | Leg squat strength (kg) |
| Change in knee extension strength | 12 weeks | Isokinetic knee extension torque |
| Change in fasting glucose | 12 weeks | Fasting glucose |
| Change in bench press strength | 12 weeks | Bench press strength (kg) |
Countries
Canada
Outcome results
None listed