COVID-19, Periodontitis
Conditions
Brief summary
Aims are to assess periodontal health and salivary stress/ immunity responses in COVID-19 survivors
Detailed description
There are lack of data concerning oral health in COVID-19 survivors, nevertheless, many middle-aged patients with oral symptoms of Post-acute COVID-19 report xerostomia and taste impairment and suffer from oral hypofunction, thus may be susceptible to periodontitis and oral frailty. Post-acute or long COVID-19 is/would be the health hallmark of post-COVID-19 era, manifested as a multiplicity of clinical problems and requiring conceptual framework aiming at multidisciplinary health preserving activities. There are various factors which may affect oral and periodontal health in post-COVID-19 era, such as disruption of dental professional care due to the fear of infection, virus-induced disturbance of oral homeostasis and, as a common denominator- COVID-19-induced psychological stress. Expected results would not just offer epidemiological data but also, mechanistic background for defining risks and modified measures aiming to preserve oral health in post-COVID-19 era.
Interventions
None listed
Sponsors
University of Belgrade
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* self-reported good general health, ≥ 14 erupted teeth excluding third molars. For periodontally healthy: Bleeding on probing score ≤10%, without attachment loss and radiographic bone loss and probing depth ≤ 3 mm in every site (Trombelli L et al., 2018). For periodontitis patients: periodontitis in stages II-IV.
Exclusion criteria
* history of periodontal treatment in previous six months, acute oral infection, presence of systemic disease(s), pregnancy, lactation, smoking ≥ 10 cigarettes per day
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal disease stage and COVID 19 | one to six months after COVID-19 | Correlation periodontitis and COVID 19 infection |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oral frailty | one to six months after COVID-19 | Oral frailty assessment in Covid 19 and Perio affected patients |
| psychological stress | one to six months after COVID-19 | Assessment of psychological stress |
| salivary stress/immunity mediators | one to six months after COVID-19 | Association of salivary stress/immunity mediators levels with perio disease in COVID 19 patients |
Countries
Serbia
Contacts
Primary ContactJelena Roganović, Professor
Outcome results
None listed