Male Infertility
Conditions
Brief summary
Use of testicular spermatozoa in non-azoospermic patients.
Detailed description
The aim of the study is to evaluate the characteristics of couples whose male partner is offered TESE after the failure of previous ICSI technique performed with ejaculated semen. All couples in a third-level University affiliated centre, between January 2010 and January 2020, whose male partner were diagnosed with any type of oligospermia and underwent TESE after ICSI from ejaculated semen, were included in the analysis.
Interventions
PROCEDURETesticular sperm extraction (TESE)
During the procedure, the testis is exposed through a small incision and one or more biopsies are taken blindly. A vertical incision is made in the median raphe, skin, dartos and tunica vaginalis to expose tunica albuginea. The tunica albuginea is incised for about 4 mm at upper pole near the head of epididymis.
Sponsors
Istituto Clinico Humanitas
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* All patients undergone testiscular sperm extraction (TESE) after failure of ICSI with the use of ejaculated sperm
Exclusion criteria
* Female age \>40 yo
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| fertilization rate (FR) | 10 years | Evaluate if there is a higher fertilization rate in male patients undergone TESE |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blastulation rate (BR) | 10 years | Evaluate if there is a higher blastulation rate in male patients undergone TESE |
| Miscarriage rate (MR) | 10 years | Evaluate if there is a lower miscarriage rate in male patients undergone TESE |
Countries
Italy
Outcome results
None listed