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Urdu Version of National Institutes of Health Stroke Scale: Reliability and Validity Study

Reliability and Validity of Urdu Version of National Institutes of Health Stroke Scale in Pakistani Stroke Population

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05203081
Enrollment
225
Registered
2022-01-24
Start date
2021-05-30
Completion date
2021-08-15
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

Stroke, Urdu version of National Institute of Health Stroke Scale, Reliability and Validity Study., Glasgow Coma Scale, Modified Rankin Scale, Barthel Index

Brief summary

The goal of this study was to translate and culturally adapt NIHSS into Urdu language and to evaluate its reliability and validity in Pakistani stroke population. Also assess its correlation with Glasgow Coma Scale, Modified Rankin Scale and Barthel Index for severity and location of post-stroke impairment.

Detailed description

As per preceding commendation, NIHSS has been translated into Urdu language from its English version and adapted culturally in Pakistan. Among stroke population, NIHSS-U has been administered in 225 patients recruited by convenience sampling technique under the pre-defined inclusion and exclusion criteria after signing consent forms. For testing inter-observer reliability and intra-observer reliability of NIHSS-U, GCS, mRS, and BI, questionnaires has been administered by two observers, on the same day, with a time interval of 2 hours between 1st and 2nd administration. As for the 3rd administration, it has been carried out after seven days by the first observer (re-testing), for intra-observer assessment. SPSS software version 24 has been used for the purpose of data entry and analysis. Internal consistency has been analyzed with Cronbach alpha value. Test-retest reliability has been assessed by using an intraclass correlation coefficient (ICC). The NIHSS-U has evaluated for content validity, construct validity, criterion validity and responsiveness.

Interventions

None listed

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
34 Years to 97 Years
Healthy volunteers
No

Inclusion criteria

* Patients or the ones next to them who gave informed consent. * Age ranges from 34 to 97 years. * Patients undertake particular stroke therapy including endovascular treatment intravenous thrombolysis.

Exclusion criteria

* Impaired strength of muscles because of cognitive and orthopedic diseases. * Patients with severe hepatic, and/or renal diseases. * Patients with impaired cognition and memory problems. * Patients whose consent was not given by themselves, their caretakers.

Design outcomes

Primary

MeasureTime frameDescription
National Institutes of Health Stroke Scale1st dayThe National Institutes of Health Stroke Scale is a standardised evaluation tool for determining the neurological impairments that are most often encountered in acute stroke patients. It measures awareness, vision, visual fields, facial weakness, extremity motor performance, sensory deficiency, coordination (ataxia), language (aphasia), speech (dysarthria), and hemi-inattention (neglect).
Glasgow Coma Scale1st dayGlasgow Coma Scale is employed for patients suffering from head injury and has three components: eye opening, verbal response, and motor response. Score ranges from 3-15, lower score stands worse outcome
Modified Rankin Scale1st dayModified Rankin Scale is use to assess the degree of remaining disabilities while recovering from stroke. In mRS, 0-6 levels stands as; 0 for no symptom at all, 1 for no significant disability, 2 for slight disability, 3 for moderate disability, 4 for moderately severe disability, 5 for severe disability, and 6 for dead.
Barthel Index1st dayBarthel Index is use to assess the level of independence and autonomy of stroke patient in performing ADLs. It is a list of 10 elementary ADLs: feeding, grooming, bathing, dressing, bowel and bladder care, toilet use, ambulation, transfers, and stair climbing. The activities are rated through time taken and assistance used by patient. Score ranges from 0-100.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026