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Effect of Aerobic Exercise Training in Obese Adults

Effect of Aerobic Exercise Training on Arterial Stiffness and Hemodynamics in Obese Adults.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05202535
Enrollment
34
Registered
2022-01-21
Start date
2021-11-15
Completion date
2022-03-15
Last updated
2022-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

Aerobic exercise, arterial stiffness, hemodynamics, obesity

Brief summary

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.

Detailed description

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.

Interventions

OTHERAerobic exercise training

Hospital-based aerobic exercise training for 15-30 minutes including pre and post-vitals assessment. 3x/week on alternate days for 8 weeks at 40-70% of HR Max

OTHERConventional therapy

Patient education and counseling with diet plan.Walking 3 days15min/day for 8 weeks

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Body mass index ≥28 kg/m² * Able to do exercise

Exclusion criteria

* Involved in structured physical activity in last 6 months * History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease) * Continuous medication use. * MSK or Neurological problems * Pregnant females

Design outcomes

Primary

MeasureTime frameDescription
Arterial Stiffness6 weeksGradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index.
Hemodynamics6 weeksFactors that govern blood flow calculated through Rate Pressure Product.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026