Lung Cancer, Lung Neoplasms, Postoperative Pain, Pulmonary Neoplasm, Thoracoscopic Surgery
Conditions
Keywords
chest tube drainage, thoracic drainage, thoracoscopic surgery, Postoperative Pain
Brief summary
Lung cancer is the leading cause of cancer-related death worldwide. Thoracoscopic pulmonary resection is a prevalent management for early stage of lung cancer. Placement of chest tube is the standard procedure after surgery, which causes pain that cannot be ignored. The investigators aimed to determine whether a muscle layer fixation of thoracic drainage tube could release postoperative pain in patients with uniport thoracoscopic pulmonary resection compared with conventional skin fixation.
Interventions
PROCEDUREmuscle layer fixation of thoracic drainage tube
The thoracic drainage tube is fixed on the muscle layer of the uniport
Sponsors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 18\<age\<80; * ASA≤III * Patients with no clinically significant cardiac history, such as ischaemic heart disease, valvular heart disease, rhythm disturbances such as frequent atrial fibrillation or premature ventricular contractions (PVCs). Patients with significant cardiac history should be optimized according the relevant guidelines before surgery is considered. * Normal cardiopulmonary function \[predicted forced expiratory volume in the first second(FEV1%) \>50% and ejection fraction (EF) \>50%of predicted value\]. Resting blood gas analysis showing arterial partial pressure of oxygen (PaO2)≥75 mmHg and arterial partial pressure of carbon dioxide (PaCO2) \<45 mmHg;
Exclusion criteria
* History of ipsilateral surgery and other conditions which can result in extensive pleural adhesion; * Coagulopathy, hypoxemia (PaO2 \<60 mmHg), hypercapnia \[arterial carbon dioxide tension(PaCO2) \>50 mmHg\]; * Significant cardiac history.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pain | From date of operation until the date of chest tube removal, assessed up to 7 days | The postoperative pain is assessed using a Visual Analog Scale (VAS) |
| Pain-associated inflammatory factor | the first day after surgery | the level of pain-associated inflammatory factor in blood, including CRP, PCT, IL6 and TNFa |
| Dosage of analgesics | From date of operation until the date of chest tube removal, assessed up to 7 days | Dosage of analgesics |
Countries
China
Outcome results
None listed