Chronic Total Occlusion of Coronary Artery, Microvascular Coronary Artery Disease, Coronary; Ischemic, Coronary Microvascular Dysfunction
Conditions
Brief summary
It is an observational study which objective is to analyze, through a series of invasive parameters, the state of the coronary microvasculature immediately after the successful percutaneous coronary intervention of a chronic total occlusion and at 6 months after the index procedure. The aim of the study is to check the variation in the values of the index of microcirculatory resistance (IMR) and invasive absolute coronary flow (AF). The working hypothesis is that, in the follow-up of these patients, AF will increase significantly with respect to its baseline and, conversely, IMR will be reduced during the follow-up.
Interventions
DIAGNOSTIC_TESTInvasive coronary physiology
Estimation of guide-wire coronary physiology parameters
Sponsors
Parc de Salut Mar
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Those patients with a clinical indication for percutaneous coronary intervention of a chronic total occlusion. As a routine clinical practice in our center, it is proposed to perform a angiographic follow-up 6 months after the index procedure.
Exclusion criteria
* No specific
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variation in the values of IMR between basal and 6-months follow-up | 6 months |
| Variation in the values of absolute coronary flow between basal and 6-months follow-up | 6 months |
Countries
Spain
Outcome results
None listed