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Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain

Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05196386
Acronym
PPP-Care
Enrollment
100
Registered
2022-01-19
Start date
2020-08-06
Completion date
2023-08-28
Last updated
2026-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-cancerous Pain, Opioid Use

Brief summary

Many treatments with WHO grade III opioids are being introduced in the rheumatology department for non-cancerous pain. The duration of this treatment prescribed at discharge is often uncontrolled and sometimes leads to significant addiction. The team at the local pain center recommends an average duration of 28 days for this type of pain. There is a full-time pharmacy intern in the rheumatology department. The aim of this work is to evaluate the impact of a targeted pharmaceutical interview on the duration of the morphine treatment initiated during hospitalization.

Interventions

BEHAVIORALAdmission conciliation interview

Previous treatment conciliation at hospital admission

BEHAVIORALDischarge conciliation interview

Allocated treatment during hospital stay

BEHAVIORALTargeted pharmaceutical interview

Specific information about treatment delivered by pharmacist

Sponsors

University Hospital, Rouen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 and \< 75 years old when entering the rheumatology department * Hospitalization in the rheumatology department * Patient with acute non-traumatic musculoskeletal disease * Patient not taking grade III opioid treatment * Patient affiliated to a social security scheme * Patient having read and understood the information letter and signed the consent form * Patient present on a day which the pharmacy intern is present

Exclusion criteria

* Presence of cancer, fibromyalgia, already diagnosed at inclusion * Patient does not understand French * Patient with Current or past opioid addiction * Person deprived of liberty by administrative or judicial decision

Design outcomes

Primary

MeasureTime frame
Total duration of opioid treatment6 months

Secondary

MeasureTime frame
Rate of patients exceeding 28 days of cumulative duration of treatment6 months
Rate of patients exceeding 90 days of cumulative duration of treatment6 months

Countries

France

Contacts

PRINCIPAL_INVESTIGATOROlivier VITTECOQ, Pr

University Hospital, Rouen

PRINCIPAL_INVESTIGATORRemi VARIN, Pr

University Hospital, Rouen

PRINCIPAL_INVESTIGATORCatherine CHENAILLER, Dr

University Hospital, Rouen

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 6, 2026