Esophageal Neoplasms
Conditions
Brief summary
In this study, data of esophageal cancer patients undergoing definitive radiotherapy in 14 institutions from various provinces in China were evaluated to help strengthen confidence in anti-cancer, including rehabilitation, economic burden, and quality of life.
Interventions
RADIATIONdefinitive radiotherapy or definitive chemoradiotherapy
A total dose of radiation therapy should be more than 50Gy
Sponsors
Chinese Academy of Medical Sciences
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients with esophageal cancer who received definitive radiotherapy (radiotherapy dose ≥50Gy) from 2015 to 2016 2. Age ≥ 18 3. The radiation field included primary esophageal tumor with or without lymph node metastasis
Exclusion criteria
1. Radiotherapy dose \< 50Gy 2. Palliative radiotherapy 3. The radiation field are metastatic areas, such as bone, brain, adrenal gland, isolated metastatic lymph nodes, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | 5 year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire module to assess quality of life (QOL) | 5 year | The EORTC QLQ-core 30 questionnaire is composed of multi-item scales and single-item measures including 5 functional scales, 3 symptom scales, a global health status-QoL scale, and 6 single items. Each of the multi-item scales includes a different set of items - no item occurs in more than 1 scale. High scale score=higher response level; a high score for a functional scale=a healthy level of function, high score for the global health status/QoL=high quality of life but a high score for a symptom scale / item=high level of symptomatology/problems. The principle for scoring these scales: 1.) Estimate the average of the items that contribute to the scale = raw score. 2.) Linear transformation to standardize the raw score, so that scores range from 0 to 100. Results should be interpreted with caution as the numbers of patients with available data over time were limited, and because of high variances as evidenced by large standard deviations. |
| Costs of treatment | 5 year | Financial burden, Whether medical insurance is affordable |
| Proportion of using chemotherapy or target therapy concurrently with radiotherapy | 2 month | Medication |
Countries
China
Outcome results
None listed