Right Ventricular Dysfunction in Septic Shock Patients in ICU

Evaluation Of Right Ventricular Function In Septic Shock Patients In Intensive Care Unit.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05193682

Acronym

Septicshock

Enrollment

Registered

2022-01-18

Start date

2022-10-31

Completion date

2023-03-31

Last updated

2022-10-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Brief summary

Assesment of right ventricular dysfunction in septic shock patients in intensive care unit.

Detailed description

Over the last decade, a few studies have highlighted the crucial role of right ventricular (RV) function in hemodynamic and respiratory diseases in critical care 1,2. However, RV failure is difficult to define in the critical care setting. A recent consensual definition proposed by different groups of experts characterizes RV failure as the association of a significant RV dilatation associated with systemic congestion 3-5. This definition is mainly physiologically based, not strictly validated, and the experts did not propose any threshold for RV size or congestion using critical care echocardiography (CCE) and central venous pressure (CVP), respectively. Fluid management in septic shock is crucial for prognosis, as fluid overload and high CVP are associated with a worse outcome 6. Septic shock is expected to impair RV function through the development of septic cardiomyopathy, but the incidence of RV failure is unknown.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Patients diagnosed with septic shock. 2. Patients will be evaluated within 24 h after diagnosis.

Exclusion criteria

1. Patients diagnosed more than 24 hours. 2. Patients with associated ischemic heart failure .

Design outcomes

Primary

Measure	Time frame	Description
Right ventricular dysfunction in septic shock patients in intensive care unit	3 years	Fluid management in septic shock is crucial for prognosis, as fluid overload and high CVP are associated with a worse outcome 6. Septic shock is expected to impair RV function through the development of septic cardiomyopathy, but the incidence of RV failure is unknown.

Outcome results