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Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery

Incidence and Risk Factors of Symptomatic Epidural Hematoma After Cervical Spine Surgery:a Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05190276
Enrollment
129
Registered
2022-01-13
Start date
2009-01-01
Completion date
2020-10-01
Last updated
2022-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic Epidural Hematoma After Cervical Spine Surgery

Keywords

epidural hematoma, cervical spine surgery, Risk factors

Brief summary

The incidence and correlation of symptomatic epidural hematomas after cervical spine surgery was reviewed and analyzed, then it will provide reference to avoid the occurrence of this complication for the future clinical work.

Detailed description

43 patients with symptomatic epidural hematoma after cervical spine surgery were enrolled in the Peking University Third hospital from January, 2009 to February, 2017. 86 patients without symptomatic epidural hematoma after cervical spine surgery during the same period were randomly selected as the control group. Demographic information (including gender, age, previous history, smoking history, etc.),disease parameters (diagnosis, mJOA(modified Japanese Orthopaedics association) score, NDI(neck disability index) score),laboratory and imaging parameters (including platelet, coagulation function, albumin, and OPLL),segments,treatment parameters (surgical method, number of surgical segments, operative time, intraoperative blood loss, anesthesia time, whether to use implants) and postoperative conditions (including the time of hematoma occurrence, diagnostic method, emergency debridement operation time, patient improvement before and after debridement) were collected.Firstly, risk factors for symptomatic epidural hematoma after cervical surgery were selected by univariate analysis,then independent risk factors were screened by multiple Logistic regression analysis.

Interventions

None listed

Sponsors

Peking University Third Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with clinically and radiologically confirmed cervical spondylosis. * Cervical spine surgery was performed in our hospital

Exclusion criteria

* Cervical trauma combined with fracture and dislocation. * Cervical cancer. * Cervical spine infection * Upper cervical spine surgery alone

Design outcomes

Primary

MeasureTime frameDescription
VAS(visual analogue pain scale)3 months after surgeryvisual analogue pain scale, to evaluate patients' pain, form 0 to 10. more scores means more pain
Frankel score3 months after surgeryPostoperative Neurological Function,From A to E. Score A means complete paralyzed and E means no paralyzed
mJOA3 months after surgeryPostoperative Neurological Function, modified Japanese orthopaedics association, From 0 to 17 scores. More scores mean better recovery after surgery. Score 0 means the most severe symptoms.

Secondary

MeasureTime frameDescription
whether patients occur hematoma after surgeryFrom post operation immediately till 3 months after surgerywhether patients occur hematoma after surgery
postoperative neurological recovery after treatment of hematomaFrom post operation immediately till 3 months after surgeryTo record neurological recovery after treatment of hematoma from post operation immediately till 3 months after surgery, use modified Japanese Orthopaedics association
whether patients need emergency debridementFrom post operation immediately till 3 months after surgerywhether patients need emergency debridement caused by hematoma
the place that occur hematomaFrom post operation immediately till 3 months after surgerythe place that occur hematoma, to locate the place of hematoma from post operation immediately till 3 months after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026