Correlation Between Elastic Modulus of Ultrasonic Shear Wave and Tumor Stromal Component in Pancreatic Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05187416

Enrollment

Registered

2022-01-11

Start date

2022-02-01

Completion date

2022-10-01

Last updated

2022-01-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Neoplasms

Keywords

2D-SWE

Brief summary

Pancreatic cancer is a gastrointestinal tumor with a high degree of malignancy. Currently, there are many first-line chemotherapy regimens in clinical practice, but the individual selection of chemotherapy regimens has not been unanimously recognized.This study is aimed at exploring the correlation between the two-dimensional shear wave elastography (2D - SWE) parameters and pancreatic cancer stromal elements proportion through an ultrasound scan for resectable pancreatic cancer cases and postoperative pathological specimen analysis. Then determine if the pancreatic cancer two-dimensional shear wave elastography can guide clinicians selecting chemotherapy scheme by predicting tumor stromal elements .These results are expected to provide an effective non-invasive diagnostic basis for individualized treatment of pancreatic cancer.

Interventions

DIAGNOSTIC_TESTtwo-dimensional shear wave elastography

Preoperative ultrasound elastography examination

Study design

Observational model

OTHER

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

1. Patients with resectable pancreatic cancer underwent ultrasound examination before surgery 2. Conventional ultrasound can clearly show pancreatic space-occupying lesions and the elastic measurements show good images 3. The patient agrees to receive ultrasound elasticity examination and signs informed consent 4. All patients had no history of radiotherapy or chemotherapy before ultrasound examination 5. All clinical case data and auxiliary examination data are complete and accessible.

Exclusion criteria

1. Ultrasound evaluation was not performed before ultrasound-guided needle biopsy 2. Conventional ultrasound could not clearly show pancreatic space-occupying lesions or poor elastic measurement images 3. Patients who refuse to accept examination or give up treatment 4. Patients receiving neoadjuvant chemotherapy or radiotherapy before ultrasound examination 5. Incomplete clinical data and auxiliary examination data.

Design outcomes

Primary

Measure	Time frame
Elastic modulus measured by Ultrasonic shear wave and tumor stromal component assessed by pathological analysis in pancreatic cancer	Baseline (Preoperative ultrasound elastography examination)

Countries

China

Contacts

Primary ContactKunlong Duan

804868814@qq.com+8617795629885

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026