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Dialyzing Wisely - Improving the Delivery of Acute Renal Replacement Therapy to Albertans

Dialyzing Wisely - Improving the Delivery of Acute Renal Replacement Therapy to Albertans

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05186636
Enrollment
9348
Registered
2022-01-11
Start date
2023-01-12
Completion date
2026-05-31
Last updated
2026-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Injury

Keywords

evidence based care pathway,, critical care medicine, quality improvement, acute renal replacement therapy

Brief summary

Implementation of an evidence-based and best practices acute RRT pathway aiming to decrease acute RRT program and healthcare systems costs while improving important patient-reported outcomes.

Detailed description

Providing acute dialysis to critically ill patients in ICU settings is resource and cost intensive. The daily costs of acute dialysis can range from $528/day for intermittent hemodialysis to $865/day for continuous renal replacement therapy. Providing acute dialysis in ICU settings requires a specialized team of nurses, educators, physicians and stakeholders to ensure its safe and effective prescription and delivery. Acute dialysis is typically delivered to some of the most acutely ill patients admitted to the ICU to support organ function and sustain life. At present, there is not a standardized approach to the prescription and delivery of acute dialysis therapy in ICUs across Alberta. The DIALYZING WISELY program will implement a standardized approach to the delivery of best practices for acute dialysis therapy to all patients who receive treatment across ICUs in Alberta.

Interventions

OTHERKPI reports

Quarterly

OTHERPrescriber reports

Individualized prescriber reports for acute RRT initiation patterns along with targeted education to ensure that align with best evidence-based practices

Sponsors

University of Alberta
Lead SponsorOTHER
Alberta Innovates Health Solutions
CollaboratorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Patient in one of 15 adult and 3 pediatric intensive care units in Alberta Receive acute RRT as part of their usual clinical care during the intervention period

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
Key performance indicators (KPI)Throughout intervention period up to 3 yearsChanges in acute KPIs
Health system costs3 yearsAcute RRT and healthcare systems costs

Secondary

MeasureTime frameDescription
Length of renal replacement therapy3 yearsLength of time patient receives RRT during their ICU stay
ICU and hospital lengths of stay3 yearsNumber of days patient spends in the ICU and hospital
ICU and 90 day mortality3 yearsnumber of patients who die before ICU discharge or within 90 days of ICU stay
Rates of RRT dependence at 90 days3 yearsnumber of patients who are receiving RRT at 90 days after ICU stay

Countries

Canada

Contacts

PRINCIPAL_INVESTIGATOROleksa Rewa, MD

University of Alberta

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 23, 2026