Stress Fracture, Vitamin d
Conditions
Brief summary
The main objective of this study is to find whether supplemental vitamin d and calcium can reduce the incidence of stress fractures in recruits. These high-risk recruits undergo intensive training which elevated bone turnover, which requires adequate level of vitamin D and calcium in order to support bone health. It is hypothesized that supplemental vitamin d and calcium will decrease the occurrence of stress fractures.
Interventions
DRUGVitamin D, Calcium
Vitamin D, calcium are available in tablets. During the 8 weeks of training, subjects were asked to take supplement tablets per day after dinner.
DRUGPlacebo
Placebo
Sponsors
Xijing Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
* Recruits newly enlisted at a training base in September 2021. * Agree to accept relevant inspections and serological research, and sign an informed consent form.
Exclusion criteria
* Suffer from diabetes, osteomyelitis and other diseases. * Suffer from claustrophobia and other MRI examination contraindications. * Long-term use of glucocorticoids, non-steroidal anti-inflammatory drugs or calcium, vitamin D. * A history of kidney disease. * Allergic to any ingredient of the medicine.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stress fracture | 3 months after the start of the basic military training. | Stress fractures were recorded when recruits reported to the clinic with suspected symptoms. All stress fractures were confirmed with radiography or Magnetic Resonance Imaging(MRI). Each subject with a stress fracture was recorded. |
Countries
China
Contacts
Primary Contactlong bi, MD,PHD
Outcome results
None listed