No Specific Condition (Patients Without Brugada Syndrome)
Conditions
Brief summary
The purpose of this study is to assess the effect of propofol induced general anaesthesia on the ST-segment of the electrocardiogram. This will be realised by retrospectively analysing the ECG-recordings from adult patients undergoing any treatment at the Catheterisation Laboratory. The ST-segment and other ECG measurements from induction of anaesthesia up to 20 minutes later, will be assessed and compared to the baseline values of the respective segments acquired before injecting propofol. It is essential in this study to exclude any patients burdened with the diagnosis, suspicion or family history of Brugada syndrome.
Interventions
OTHERObservational study
Retrospective data-analysis
Sponsors
Universitair Ziekenhuis Brussel
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Induction of anaesthesia with propofol * Monitored anaesthesia in the CathLab of the Universitair Ziekenhuis Brussel
Exclusion criteria
* Brugada Syndrome or family history of Brugada syndrome * Paediatric population (age \<18) * Patients who did not receive propofol during the procedure * Patients who presented with fever (central core temperature \>38,0°C)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ST-segment variations after propofol administration. | Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol | Determine ST-segment variations in mm (either augmentation or suppression) on the ECG in the 20 minute period after administration of propofol in comparison to the baseline ECG |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Additional ECG-segment variations after propofol administration | Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol | Assess additional ECG-segments measurements in mm and ms from the ECGs recorded. These include Jp- (mm), QRS- (ms), T(p-e)-segments (ms) and the T(p-e)/QT ratio. |
Countries
Belgium
Outcome results
None listed