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Natural Course and Prognosis of Hospitalized Patients With Cirrhosis

Natural Course and Prognosis of Hospitalized Patients With Cirrhosis: a Prospective, Multicenter, and Observational Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05185154
Enrollment
336
Registered
2022-01-11
Start date
2021-11-01
Completion date
2025-10-31
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis

Brief summary

The aim of this prospective study is to evaluate the natural course and prognosis of hospitalized patients with liver cirrhosis.

Detailed description

The aim of this prospective study is to collect data on hospitalized patients with liver cirrhosis at four institutions in Korea (Kangbuk Samsung Hospital, Hallym University Dongtan Sacred Heart Hospital, Chosun University Hospital, and National Medical Center). If patients agree to participate in this clinical trial, the patients' data (such as age, sex, height, weight, nutrition status \[RFH-NPT\], history of medication, laboratory findings, endoscopic findings, and radiologic findings) will be collected in a research database. The research database will be updated, every 6 months, to include data on patients' disease outcomes and follow-up care.

Interventions

None listed

Sponsors

Kangbuk Samsung Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Hospitalized patients with liver cirrhosis * Admission to the hospital because of cirrhotic complications such as uncontrolled ascites, variceal bleeding, hepatic encephalopathy, hepatorenal syndrome, spontaneous bacterial peritonitis, hepatocellular carcinoma, acute kidney injury, bacterial infection, acute liver failure, and etc.

Exclusion criteria

* Admission to the hospital without cirrhotic complications * Patients who refuse the follow-up of outpatient department

Design outcomes

Primary

MeasureTime frameDescription
All-cause mortalityUp to 2 yearsDeath from any cause
Liver-related mortalityUp to 2 yearsDeath from liver disease

Secondary

MeasureTime frameDescription
Cause of admission to hospitalAt baselinePrevalence of cause of admission to hospital

Countries

South Korea

Contacts

Primary ContactWon Sohn, MD, PhD
hand0827@naver.com82-2-2001-2557

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026