Postoperative Recovery, Progression
Conditions
Brief summary
A single-center study on the effect of systemic/selective lymph node dissection on the prognosis of ground glass nodules smaller than 3cm and with components with consolidation/tumor ratio between 0.5-1
Detailed description
A single-center study on the effect of systemic/selective lymph node dissection on the prognosis of ground glass nodules smaller than 3cm and with components with consolidation/tumor ratio between 0.5-1
Interventions
selective lymph node dissection
OTHERSystemic Lymph Node Dissection
Systemic Lymph Node Dissection
Sponsors
Shanghai Zhongshan Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Masking description
open label
Intervention model description
systemic or selective lymph node dissection group
Eligibility
Sex/Gender
ALL
Age
25 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Patients enrolled in the study must meet all of the following conditions: * 1.Aged between 25 and 75 years; * 2\. GGO is diagnosed by thin-section lung CT (thickness \<1.5mm) within one month before surgery; * 3\. The maximum diameter of the GGO is smaller than 3cm; * 4\. The solid component in GGO between 50%-100%; * 5\. Preoperative examination showed that the patient could tolerate lobectomy; * 6\. The patient is able to understand and comply with the study and has provided written informed consent.
Exclusion criteria
Patients meeting any of the following criteria are not eligible for this trial: * 1\. Patients with a history of lung surgery; * 2\. Postoperative pathology showed non-primary lung cancer; * 3\. The scope of surgical resection is larger than one lung lobe; * 4\. Patients with a history of other tumors; * 5\. Patients with severe complications (coronary heart disease, valvular heart disease, end-stage renal disease, severe liver cirrhosis); * 6\. Unable to cooperate with the researchers because of dementia or cognitive decline * 7\. Other situations that are not in conformity with the standards and requirements of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | From enrollment to 36 months after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complications | 1-2 Weeks after enrollment (after Surgery) | The degrees of cough |
Outcome results
None listed