Splenectomy; Status
Conditions
Keywords
Pediatrics, Non-malignant hemoglobinopathies, Comprative effectivness, Partial Splenectomy, Total Splenectomy
Brief summary
Partial splenectomy or total splenectomy are the two surgical treatment of non-malignant hemoglobinoptahie. The aim of this treatment is to decrease transfusion. The main risk is infectious in total splenectomy, that's why partial splenectomy was suggest. But the efficiency of partial splenectomy decrease over time and a totalisation could be mandatory.
Interventions
None listed
Sponsors
University Hospital, Montpellier
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Children between 0- 18 years olds * Total or partial splenectomy * Non malignant hémoglobinopathies
Exclusion criteria
\- Total or partial splenectomy outside of non malignant hemoglobinopathies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Compared the effectiveness with the number of transfusion | Day 1 | Compared the effectiveness with the number of transfusion after the surgery between total and partial Febrile urinary tract infection was defined as a positive urine examination with a single bacteria with more than 10.5 cfu/mL and more than 10.4 leukocytes/ml associated with fever above 38.5°C and C-reactive protein (CRP) above 50 mg/ |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of infectious event in total and partial splenectomy | Day 1 | Number of infectious event in total and partial splenectomy |
| number of totalisation in partial | Day 1 | number of totalisation in partial |
Countries
France
Contacts
Primary ContactNicolas KALFA, MD
Backup ContactBenoit Tessier, Student
Outcome results
None listed