Lung; Node
Conditions
Keywords
Lung nodule, Localization, Coil, Needle
Brief summary
Preoperative computed tomography-guided localization can improve technical success rates associated with sublobar lung nodule resection conducted via video-assisted thoracoscopic surgery. This study sought to compare the clinical efficacy of computed tomography-guided localization needle and coil insertion as approaches to preoperative lung nodule localization.
Detailed description
Lung nodules are frequently diagnosed and often exhibit a high potential for malignancy such that they are commonly diagnosed and treated via video-assisted thoracic surgery approaches. Preoperative computed tomography-guided localization strategies are commonly employed to improve the successful rate of video-assisted thoracic surgery-guided sublobar (wedge or segmental) resection procedures. One recent meta-analysis found coil localization to be associated with the lowest rate of complications of tested localization materials. Hook-wire has also been widely used due to its simple placement approaches. However, a number of recent reports have suggested that hook-wire insertion approaches are associated with an increased potential for frequent and potentially severe complications. The use of a novel lung nodule localization needle strategy based on the modification of this previously described hook-wire approach has recently been employed in clinical contexts. Such localization needles have the potential to incur lower rates of detachment and complications relative to the hook-wire strategy without resulting in an increase in localization difficulty. The relative clinical efficacy of localization needle-based strategies compared to that of other localization materials, however, has yet to be established in the context of lung nodule localization.
Interventions
A localization needle which is used for preoperative localization of lung nodules.
A coil which is used for preoperative localization of lung nodules.
Sponsors
Study design
Eligibility
Inclusion criteria
1. Patients with lung nodules; 2. Patients with an intermediate-to-high risk of malignancy as established based upon radiological and clinical findings.
Exclusion criteria
1. Lung nodule \< 5 mm; 2. Calcification nodules; 3. Lung nodule which decreased in size at time of follow-up; 4. Patients with distant metastases or other severe comorbidities.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Technical success of localization | From the date of randomization until the date of first documented failure localization from any cause, assessed up to 7 day. | Lung nodule localization is considered technically successful if the coil tail or marked line can be visible during the video-assisted thoracoscopic surgery. procedure |
Countries
China