Skin Condition, Sleep Disturbance
Conditions
Brief summary
To assess Collagen Drink on skin condition and sleep quality improvement
Interventions
DIETARY_SUPPLEMENTPlacebo drink
Blank
DIETARY_SUPPLEMENTCollagen Juice Drink
Testing product
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged above 20 years old
Exclusion criteria
* Subject who is not willing to participate in this study. * Patients with diseases of the skin, liver, kidney. * Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder. * Female who is pregnant or nursing * Constant drug use * Received facial laser therapy, chemical peeling or UV overexposure (\>3 hours everyday) in the past 4 weeks. * Students taught by the PI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of desmosine of blood | Change from Baseline desmosine at 8 weeks | Venous blood was sampled to measure desmosine |
| The change of skin wrinkles | Change from Baseline skin wrinkles at 8 weeks | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units |
| The change of skin texture | Change from Baseline skin texture at 8 weeks | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units |
| The change of skin collagen density | Change from Baseline skin collagen density at 8 weeks | DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units |
| The change of skin elasticity | Change from Baseline skin elasticity at 8 weeks | Cutometer® MPA580 was utilized to measure skin elasticity. Units: arbitrary units |
| The change of skin L* value | Change from Baseline L* value at 8 weeks | Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100 |
| The change of TIMP-1 of blood | Change from Baseline TIMP-1 at 8 weeks | Venous blood was sampled to measure TIMP-1 |
| The change of sleep quality | Change from Baseline sleep quality at 8 weeks | Self-assessment questionnaire was utilized to survey sleep quality. |
| The change of AGEs of blood | Change from Baseline AGEs at 8 weeks | Venous blood was sampled to measure AGEs |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of skin pores | Change from Baseline skin pores at 8 weeks | VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units |
| The change of skin a* value | Change from Baseline skin a* value at 8 weeks | Chroma Meter MM500 was utilized to measure skin a\* value. Units: arbitrary units |
| The change of skin hydration | Change from Baseline skin hydration at 8 weeks | Corneometer® CM825 was utilized to measure skin hydration. Units: arbitrary Corneometer® units 0-120 |
| The change of transepidermal water loss | Change from Baseline transepidermal water loss at 8 weeks | Tewameter® TM300 was utilized to measure skin hydration. Units: g/hm² |
| The change of skin melanin index | Change from Baseline skin melanin index at 8 weeks | Soft Plus was utilized to measure skin melanin index. Units: arbitrary units |
Countries
Taiwan
Outcome results
None listed