Stellate Block Versus Nimodipine Infusion for Traumatic Brain Injury

Ultrasound-guided Stellate Ganglion Block Versus Nimodipine Infusion for Enhancement of Cerebral Blood Flow in Traumatic Brain Injury

Status

UNKNOWN

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05182619

Enrollment

Registered

2022-01-10

Start date

2022-01-01

Completion date

2023-04-01

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic Brain Injury

Brief summary

the study is designed to perform an intervention for enhancement of cerebral blood flow in patients with traumatic brain injury showing vasospasm through transcranial doppler

Interventions

PROCEDUREultrasound-guided stellate ganglion block

under aseptic conditions, using the ultrasound guidance, bilateral stellate ganglion block will be done using bupivacaine and betamethasone mixture, 8 ml volume will be given for each side

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients more than 18 ys old with isolated head trauma and traumatic brain injury

Exclusion criteria

* • Hemodynamic instability (mean ABP less than 70 mmHg) * History of severe systemic disease including cardiopulmonary failure or hepatorenal failure * Allergy to local anesthetics * Coagulation disorders * Abnormal neck structures disturbing normal anatomy as neck tumors

Design outcomes

Primary

Measure	Time frame	Description
enhancement of cerebral blood flow	one week	increased blood flow through middle cerebral artery and basilar artery measured by transcranial doppler ultraound

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026