Analgesia for Thyroidectomy Using Bilateral Superficial Cervical Plexus Block With Bupivacaine Only or Adding Ketorolac to it.

The Effect of Adding Ketorolac to Bupivacaine in Superficial Cervical Plexus Block in Thyroid Surgery.

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05180214

Enrollment

Registered

2022-01-06

Start date

2021-01-17

Completion date

2021-09-15

Last updated

2022-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Goiter, Thyroid Nodule

Keywords

ketorolac, superficial cervical plexus block, thyroidectomy

Brief summary

Thyroidectomy is considered a common operation with moderate to severe postoperative pain in some patients. Patients are divided into two groups. Bupivacaine group received bilateral superficial cervical plexus block (BSCPB) with 10 ml of bupivacaine (0.25%) and 1 ml of normal saline on each side and the Bupivacaine Ketorolac group received (BSCPB) with 10 ml of bupivacaine (0.25%) and 1 ml of ketorolac (15 mg) on each side.

Interventions

DRUGBupivacain

analgesic

DRUGKetorolac

analgesia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Patients aged 20-50 years * ASA I-II patients * Patients going to do thyroid surgeries under general anesthesia

Exclusion criteria

* Patient refusal * Known history of sensitivity to the drug used in the study * Drug abuse * Infection at the site of the block * Presence of coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
1st analgesic requirement	24 hours	The first time of supplemental analgesic need postoperatively

Secondary

Measure	Time frame	Description
analgesic consumption	24 hours	total analgesic consumption
postoperative pain	24 hours	visual analogue scale(0-10) 0=no pain and 10=severe intolerable pain

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026