Association of Bisphenol A,Paraben Exposure and Type 2 Diabetes

The Possible Association Between Bisphenol A, Paraben Exposure and Type 2 Diabetic Adult Patients.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05177250

Enrollment

100

Registered

2022-01-04

Start date

2022-02-20

Completion date

2023-01-31

Last updated

2022-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type2 Diabetes, Bisphenol A

Brief summary

The aim of this study is to evaluate the association between BPA , paraben levels and type 2 DM patients

Detailed description

The first phase of the study will include a questionnaire : * The cases and control will be asked about demographic information such as residence, age, education, and occupation. * History of discovery of diabetes. * Exposure to products and materials such as polycarbonate plastics, cosmetics and beverages containing bisphenol A and paraben and it will be evaluated through exposure sheet through asking about dietary exposure, Environmental exposure and medical exposure. Then clinical evaluation including: * Full clinical examination will be performed for cases and control. * Anthropological data: their weights, heights and waist circumference will be measured. The body mass index (BMI) will be calculated by weight (kg)/height (m)2 formula. * Investigations: routine and specific investigation as blood glucose level, HbA1c and lipid profile. * Urine specimens will be collected in clean, glass containers will labeled with the subject identification number. Turbid sample or those containing blood will be excluded. * All specimens will be stored frozen below 20 degree centigrade. * Urine samples will be analyzed by High Performance liquid chromatograph (HPLC) to detect bispenol A and parabens levels.

Interventions

DEVICEHPLC

taking urine samples from participants and analyze these samples to detect bisphenol A and paraben

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Adult patients ( 18 y or elder). 2. Type 2 DM

Exclusion criteria

* Type 1 DM * Less than 18 y * History of chronic diseases such as liver failure, cardiac patients……etc

Design outcomes

Primary

Measure	Time frame	Description
Bisphenol A and paraben detection in urine samples of diabetic (n=50) and non diabetic persons (n=50)	Baseline	Evaluation of bisphenol A and Paraben detection in urine samples from type 2 diabetic adult patients compared with non diabetic persons using HPLC

Countries

Egypt

Contacts

Primary ContactAhmed Awad, PHD

Drahmedfathy8090@kasralainy.edu.eg201063348234

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026