Association of Bisphenol A,Paraben Exposure and Type 2 Diabetes

The Possible Association Between Bisphenol A, Paraben Exposure and Type 2 Diabetic Adult Patients.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05177250

Enrollment

100

Registered

2022-01-04

Start date

2022-02-20

Completion date

2023-01-31

Last updated

2022-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bisphenol A, Type2 Diabetes

Brief summary

The aim of this study is to evaluate the association between BPA , paraben levels and type 2 DM patients

Detailed description

The first phase of the study will include a questionnaire : * The cases and control will be asked about demographic information such as residence, age, education, and occupation. * History of discovery of diabetes. * Exposure to products and materials such as polycarbonate plastics, cosmetics and beverages containing bisphenol A and paraben and it will be evaluated through exposure sheet through asking about dietary exposure, Environmental exposure and medical exposure. Then clinical evaluation including: * Full clinical examination will be performed for cases and control. * Anthropological data: their weights, heights and waist circumference will be measured. The body mass index (BMI) will be calculated by weight (kg)/height (m)2 formula. * Investigations: routine and specific investigation as blood glucose level, HbA1c and lipid profile. * Urine specimens will be collected in clean, glass containers will labeled with the subject identification number. Turbid sample or those containing blood will be excluded. * All specimens will be stored frozen below 20 degree centigrade. * Urine samples will be analyzed by High Performance liquid chromatograph (HPLC) to detect bispenol A and parabens levels.

Interventions

DEVICEHPLC

taking urine samples from participants and analyze these samples to detect bisphenol A and paraben

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Adult patients ( 18 y or elder). 2. Type 2 DM

Exclusion criteria

* Type 1 DM * Less than 18 y * History of chronic diseases such as liver failure, cardiac patients……etc

Design outcomes

Primary

Measure	Time frame	Description
Bisphenol A and paraben detection in urine samples of diabetic (n=50) and non diabetic persons (n=50)	Baseline	Evaluation of bisphenol A and Paraben detection in urine samples from type 2 diabetic adult patients compared with non diabetic persons using HPLC

Countries

Egypt

Contacts

Primary ContactAhmed Awad, PHD

Drahmedfathy8090@kasralainy.edu.eg201063348234

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026