Severe Pre-eclampsia
Conditions
Brief summary
Changes in the optic nerve sheath diameter detected by ultrasound are considered an important manifestation of increased intracranial pressure . The normal optic nerve sheath diameter measures up to 5.0 mm and an average optic nerve sheath diameter more than 5 mm is considered abnormal and elevated intracranial pressure should be suspected.Cerebral edema have been demonstrated in 71% to 100% of magnetic resonance imaging in preeclamptic patients and an increase in optic nerve sheath diameter has been described in preeclamptic females compared to healthy pregnant females Therefore, Increased optic nerve sheath diameter can indirectly reflect the state of intracranial edema that could be a part of generalized edema of preeclampsia and it could be a possible marker of generalized tissue edema and fluid overload in these patients.
Interventions
RADIATIONultrasound
ultrasonographic assessment of optic nerve sheath diameter
Sponsors
Sohag University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Systolic blood pressure of 160mm Hg or higher, or diastolic blood pressure of 110mm Hg or higher on 2 occasions at least 6 hours apart on bed rest. * Proteinuria ≥5g in a 24 hour urine specimen or ≥3+ on 2 random urine samples collected at least 4 hours apart. * patient acceptance * Accepted mental state of the patients
Exclusion criteria
* patient refusal to participate in the study * chronic kidney disease * chronic pulmonary disease * chronic cardiac disease * chronic hypertension * previous ocular operation and diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| correlation between optic nerve sheath diameter and extravascular lung water | up to 24 hours | correlation between ultrasound assessment of optic nerve sheath diameter and extravascular lung water |
Countries
Egypt
Contacts
Primary ContactHossam Eldin Hassan ahmed, assisstant lecturer
Outcome results
None listed