Skip to content

Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used

Comparison of Povidone Iodine and Hypochlorous Acid Used as a Preoperative Antiseptic in Neonatal Circumcision

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05175027
Enrollment
60
Registered
2022-01-03
Start date
2021-05-05
Completion date
2021-11-11
Last updated
2022-01-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Newborn; Infection, Disinfection, Circumcision

Keywords

circumcision,, wound, antibacterial

Brief summary

Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups. Before the circumcision procedure, asepsis is provided with a surface disinfectant. Various methods can be used for this process. Povidone iodine, which has been used for years during the transition from traditional circumcision methods to surgical circumcision methods; tissue damage, allergic reactions and increase in pain level. For this reason, the investigators aimed to compare it with Hypochlorous acid (Crystalin), which is a less toxic and more physiological antiseptic solution. Material and Method: Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group. At the beginning of the circumcision procedure, a culture was taken in the form of a prepucial swab 1 minute after the cleaning of the local area and the inner surface of the prepuce. Then circumcision was performed. Culture results and complications were compared.

Detailed description

It is aimed to compare two solutions used for cleaning the operation area in newborn circumcision.It was conducted to compare the antibacterial activity of povidone iodine and hypochlorous.

Interventions

Randomize

Sponsors

Hisar Intercontinental Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Intervention model description

Two models:Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group.

Eligibility

Sex/Gender
MALE
Age
1 Days to 1 Months
Healthy volunteers
Yes

Inclusion criteria

* male * newborn,

Exclusion criteria

* hipospadias, * epispadias, * urinary infectious

Design outcomes

Primary

MeasureTime frameDescription
The effect of both drugs on antibacterial effects will be investigatedone weekthere is bacterial growth:1, there is no bacterial growth:0
The effect of both drugs on wound healing will be investigated.one monththere is wound healing;1,no wound healing:0

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026