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Malnutrition Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Evaluation of Malnutrition in Patients Undergoing Major Abdominal Surgery Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05174715
Enrollment
260
Registered
2022-01-03
Start date
2017-01-01
Completion date
2020-07-15
Last updated
2022-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Keywords

malnutrition, sarcopenia, GLIM criteria

Brief summary

Evaluation of malnutrition with the help of the GLIM criteria. Muscle mass measurement, as recommended in the GLIM criteria was done with the help of abdominal CT scan and BIA. Both methods were compared and their association to the clinical outcome was assessed.

Detailed description

We retrospectively analysed 260 patients undergoing major abdominal surgery between January 2017 and December 2019. Patients were prospectively screened and assessed for malnutrition with Nutritional Risk Score (NRS) and Subjective Global assessment (SGA). Body composition was analysed with CT scan and BIA within 30 days before surgery. GLIM criteria were retrospectively determined referring to the Fat free Mass from BIA (FFMBIA) and Muscle Mass from axial CT scan at lumbar level 3 (MMCT). The prevalence of GLIM - malnutrition according to BIA and CT was evaluated. Multivariate logistic regression analysis was used to determine association between malnutrition and outcome parameters. ROC-curves specified sensitivity and specificity of the different tools and areas under the curve were calculated.

Interventions

OTHERBIA

nutritional status was evaluated using BIA

Sponsors

Klinikum St. Georg gGmbH
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* age above 18 years * BIA and CT scan was available within 31 days before surgery * patients undergoing major abdominal surgery for gastrointestinal cancer

Exclusion criteria

* patients who were not able to agree to the participation * missing assessment of the nutritional status * leck of quality of the CT scan

Design outcomes

Primary

MeasureTime frameDescription
overall complications31 days PODall complications perioperatively including surgical side infections, anastomic leakage, sepsis

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026