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A University-Community Partnership to Reduce Exposure to Disinfection Byproducts In Appalachia

A University-Community Partnership to Reduce Exposure to Disinfection Byproducts In Appalachia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05172752
Enrollment
200
Registered
2021-12-29
Start date
2022-02-25
Completion date
2026-10-01
Last updated
2026-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disinfection By-products

Keywords

Community-engaged, Appalachia

Brief summary

Appalachian Kentuckians in Martin and Letcher Counties are grappling with a health-threatening drinking water crisis arising from exposures to disinfection by-products (DBPs). DBPs include trihalomethanes (THMs), haloacetic acids (HAAs), chlorate, and other compounds that have been associated with a variety of adverse health effects, including increased risk of bladder cancer and cardiovascular birth defects. This study implements a multi-stakeholder, multi-method approach to improve understanding of, characterize spatial and temporal variations in, and reduce exposure to DBPs in these Appalachian Kentucky counties.

Interventions

OTHERCitizen Scientist Training Program

Citizen Scientist Training Program Participants is a three year training and in-home sampling program for disinfection byproducts. Participants will be trained and assessed based on their experience in the training program.

OTHERStakeholder Consultation Core Program

Stakeholder Consultation Core Program Participants is a five year assessments where participants will participate in quarterly meetings and deliberative activities related to disinfection byproducts. Participants will be assessed based on their experience in the program.

Sponsors

Anna Hoover
Lead SponsorOTHER
National Institute of Environmental Health Sciences (NIEHS)
CollaboratorNIH

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Located in Martin or Letcher County water districts * At least 18 years old * Able to read/speak in English

Exclusion criteria

* Located outside of Martin or Letcher County water districts

Design outcomes

Primary

MeasureTime frameDescription
Change in Environmental Health Literacy (EHL) - KnowledgeBaseline, 5-yearsStudy participants will complete pre-/post-surveys of disinfection byproducts-related knowledge. Participants will answer 21 questions with multiple choice or fill in the blank response options that will be assessed for correctness/completeness.
Change in Environmental Health Literacy (EHL) - Attitudes/BehaviorsBaseline, 5-yearsStudy participants will complete pre-/post-surveys of disinfection byproducts-related attitudes. Participants will answer 9 questions related attitudes/behaviors with a five-point Likert scale, ranging from Strongly Disagree to Strongly Agree, where Strongly Agree indicates a greater likelihood for the behavior/more positive attitude.
Change in participant network densityBaseline, 5-yearsThe proportion of direct ties within the network as compared to the number of possible ties as measured by an unbounded social media analysis.
Change in participant centralityBaseline, 5-yearsThe influence of each individual within the network (i.e., betweenness and degree centrality) as measured by an unbounded social media analysis.
Change in participant reciprocityBaseline, 5-yearsThe number of reciprocal ties, which is the extent to which individuals within the network recognize each other as valued resources/collaborators as measured by an unbounded social media analysis.

Countries

United States

Contacts

CONTACTAnna Hoover, PhD
Anna.Hoover@uky.edu859-218-0343
CONTACTJason Unrine, PhD
jason.unrine@uky.edu859-257-1657
PRINCIPAL_INVESTIGATORAnna Hoover, PhD

University of Kentucky

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 28, 2026