Mild Cognitive Impairment, Parkinson Disease
Conditions
Keywords
Dual-task walking training, Parkinson's disease, Mild cognitive impairment, Electroencephalography
Brief summary
The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.
Interventions
BEHAVIORALIntegrated physical-cognitive training
Perform a postural task and a cognitive task at the same time (dual-task model) 70 minutes/session\*2 sessions/week\*6 weeks
BEHAVIORALConsecutive physical-cognitive training
Perform a postural task and a cognitive task separately for identical durations 70 minutes/session\*2 sessions/week\*6 weeks
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* a diagnosis of idiopathic Parkinson's disease * have decreased cognitive functions but do not interfere with functional independence * Montreal Cognitive Assessment (MoCA): 21-25 * able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°
Exclusion criteria
* a diagnosis of dementia * other diseases that may influence cognitive functions or walking performance * a history of brain surgery * modification of the medication during the exercise intervention
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline dual-task walking performance at 8 weeks | 8 weeks | — |
| Fall frequency | 20 weeks | — |
| Change from baseline Montreal Cognitive Assessment (MoCA) score at 8 weeks | 8 weeks | MoCA: 0-30 points, higher scores mean a better outcome |
Countries
Taiwan
Outcome results
None listed