Cirrhosis
Conditions
Keywords
cirrhotic trauma
Brief summary
Given that there are only a few studies on the effects of cirrhosis on trauma patients and none have addressed the impact cirrhosis has on the incidence of infections, it is important that we study this to determine the mortality in cirrhotic trauma patients and ascertain the incidence of infectious complications in these patients. We hypothesize that trauma patients with cirrhosis will have higher rates of mortality and infectious complications.
Detailed description
There have been a select few studies addressing the effects of cirrhosis on trauma patients. These studies show an increase in morbidity and mortality. However, there is limitation in the depth and breadth of analysis. The primary aim of this study is to determine the mortality rates in cirrhotic trauma patients with a secondary end-point being the determination of the incidence of infections associated with these patients. Given that there are only a few studies on the effects of cirrhosis on trauma patients and none have addressed the impact cirrhosis has on the incidence of infections, it is important that we study this to determine the mortality in cirrhotic trauma patients and ascertain the incidence of infectious complications in these patients. PI hypothesizes that trauma patients with cirrhosis will have higher rates of mortality and infectious complications.
Interventions
None listed
Sponsors
Methodist Health System
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Cirrhotic trauma patients in the United States within 2010-2018 * Patients ≥ 18 years old
Exclusion criteria
* Patients less than 18 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | 2010-2018 | Patient death |
| Incidence of infectious complications | 2010-2018 | Incidents of complications with infections |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient demographics | 2010-2018 | demographics of patients |
| vital signs; clinical measurements | 2010-2018 | clinical measurements |
| vital signs; pulse rate | 2010-2018 | pulse rate (bpm) |
| vital signs; temperature | 2010-2018 | temperature |
| vital signs; respiration rate | 2010-2018 | respiration rate |
| vital signs; blood pressure | 2010-2018 | blood pressure |
| injury characteristics | 2010-2018 | characteristics of injuries |
| hospital and ICU lengths of stay | 2010-2018 | length of days patients stays in hospital/ICU |
| transfusion data | 2010-2018 | data regarding transfusions |
| alcohol use indicator | 2010-2018 | indicator of alcohol use |
| drug use indicator | 2010-2018 | indicator of drug use |
| ventilator days | 2010-2018 | days on ventilator |
| Abbreviated Injury Scale | 2010-2018 | abbreviated injury scale score |
| Glasgow Coma Scale | 2010-2018 | glasgow coma scale score |
| Injury Severity Score | 2010-2018 | score of injury |
| discharge date | 2010-2018 | date of discharge |
| arrival date | 2010-2018 | date of arrival |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORParvez Mantry, MD
The Methodist Hospital Research Institute
Outcome results
None listed