Erector Spinae Plane Block
Conditions
Keywords
Erektor Spinae Plane Block, Postoperative Analgesia, Surgical Stress Response
Brief summary
Our study aimed to examine the effects of ultrasound guided erector spinae plane block in radical prostatectomy surgery on pain and surgical stress response, to reduce adrenocortical and sympathetic discharge due to anesthesia and surgery, and to reduce peroperative opioid analgesic consumption.
Detailed description
In this study 46 patients between the ages of 30-74, American Society of Anesthesiologists (ASA) score I-II and undergoing radical prostatectomy surgery at T.R. Ministry Of Health İstanbul Göztepe Prof. Dr. Süleyman Yalçın City Hospital were included. The patients were randomly divided into two groups as ESPB applied Group B (n=23) and not Group K (n=23). Patient-controlled analgesia (PCA) was initiated in all patients for postoperative analgesia. Patients' demographic data (age, gender, ASA score), intraoperative hemodynamic data, intraoperative and postoperative additional narcotic consumption, postoperative Numeric Rating Scale (NRS) scores (postoperative 0, 5 and 20 minutes and Then, 1, 3, 6, 12, 18 and 24 h), postoperative nausea-vomiting scores and possible complications related to block and / or surgery were recorded.Intraoperative MAP, HR, SpO2, BIS values of patients in both groups were recorded every 5 minutes. Blood glucose, insulin, cortisol, prolactin and C-reactive protein (CRP) were studied three times; preop morning at 6:00, intraoperative when surgical incision closing and postoperative 24h. in order to evaluate the surgical stress response in the patients.
Interventions
PROCEDUREESP block
Before general anesthesia, ESP block was applied from the T12 vertebra level with 10 ml 0.5% bupivacaine HCL 5 ml 2% lidocaine HCL 5 ml 0.9% isotonic NaCl mixture
Sponsors
Istanbul Medeniyet University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
30 Years to 74 Years
Healthy volunteers
No
Inclusion criteria
* ASA I-II
Exclusion criteria
* diabetes * coagulopathy * local anesthetic * drug allergy * long hospitalization history, * hormone disorder * advanced organ failure * history of steroid use * vertebral anomalies * mental retardation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| insulin | postoperative 24 hours. | µIU/mL |
| Numeric Pain Scale | postoperative 24 hours. | Between 1-10. 1: no pain, 10: worst possible pain |
| Blood glucose | postoperative 24 hours. | mg /dL |
| C-reactive protein | postoperative 24 hours. | mg/L |
| cortisol | postoperative 24 hours. | µg/dL |
| prolactin | postoperative 24 hours. | µg/L |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Remifentanil Consumption Speed | 3 hours | µg /kg/dk |
Countries
Turkey (Türkiye)
Outcome results
None listed