Lower Uterine Segment Following a Cesarean Section With Barbed Suture

Lower Uterine Segment at the Next Pregnancy Following a Cesarean Section With Barbed Suture: an Observational Prospective Comparative Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05166174

Acronym

BARB-LOWSEGM

Enrollment

Registered

2021-12-21

Start date

2019-01-01

Completion date

2021-10-01

Last updated

2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section Complications, Cesarean Wound; Dehiscence

Keywords

barbed suture, uterine lower segment, cesarean section

Brief summary

This aim of this study is to investigate the LUS in the pregnancy following a previous cesarean section with the use of barbed or conventional smooth suture.

Detailed description

To better assess the risk of uterine rupture, some authors have proposed sonographic measurement of lower uterine segment (LUS) thickness near term, assuming that there is an inverse correlation between LUS thickness and the risk of uterine scar defect. Recently, barbed suture has been employed for closing uterine wall after cesarean section, demonstrating the reduction of closure time of the uterine incision and estimated blood loss. Until now, the impact of barbed suture in future pregnancies has not been investigated.

Interventions

PROCEDURETransvaginal ultrasound in the third trimester pregnancy

Ultrasonographic transvaginal exam in patients at third trimester pregnancy (34-38 weeks of gestation)

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* pregnant women * being undergone a previous elective cesarean section at term of pregnancy (more than 37 weeks of gestation), in which barbed or conventional smooth suture was used for closing anterior uterine wall

Exclusion criteria

* having done more than one cesarean section * having done a previous urgent cesarean section * having done previous uterine surgical procedures with exception than one cesarean section

Design outcomes

Primary

Measure	Time frame	Description
Ultrasonographic measure of lower uterine segment thickness	34-38 weeks following study enrollment	Measure of lower uterine thickness (mm) at transvaginal ultrasound

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026