Effect of Sodium Alendronate on the Final Implant Stability.

Effect of Sodium Alendronate Versus Sticky Bone as Socket Preservation Materials on the Final Implant Stability. A Randomized Clinical Trial

Status

UNKNOWN

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05162885

Enrollment

Registered

2021-12-17

Start date

2021-05-01

Completion date

2022-10-01

Last updated

2021-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Labial Wall Defect

Keywords

Stability, Sodium Alendronate, Implant, Sticky bone

Brief summary

evaluation of the final implant stability after its placement in sockets preserved with two different socket preservation materials

Detailed description

compare the stability of implant placement using Osstell ISQ resonance frequency analyzer, and marginal bone resorption and bone density around implant by X-ray analysis in different socket preservation techniques comparing sodium alendronate with the sticky bone graft technique

Interventions

PROCEDURESocket Preservation technique

Implant placement after Socket preservation Technique with sodium alderonate versus sticky bone in salama&salama Class 3 labial wall defect

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients with seeking implant drive prosthesis after socket has been preserved by either technique. * Patients with seeking implant drive prosthesis with Salama Class 3 defective sockets. * Both genders males and females will be included.

Exclusion criteria

* General contraindications to implant surgery. * Patient seeking immediate implant placement. * Subjected to irradiation in the head and neck area less than 1 year before implantation. * Untreated periodontitis. * Poor oral hygiene and motivation. * Uncontrolled diabetes. * Pregnant or nursing. * Substance abuse. * Psychiatric problems or unrealistic expectations. * Severe bruxism or clenching. * Immunosuppressed or immunocompromised. * Treated or under treatment with intravenous amino-bisphosphonates. * Active infection or severe inflammation in the area intended for implant placement. * Unable to open mouth sufficiently to accommodate the surgical tooling. * Patients participating in other studies, if the present protocol could not be properly * followed. Referred only for implant placement or unable to attend a 5-year follow-up

Design outcomes

Primary

Measure	Time frame	Description
Implant stability	3-4 months after Dental implant placement	Calculate the final implant stability of two groups using Osstell resonance frequency analyzer

Secondary

Measure	Time frame	Description
marginal bone	3-4 months after Dental implant placement	Evaluation of marginal bone resorption around implant in two groups using superimposition x-ray (CBCT) software analysis

Other

Measure	Time frame	Description
Bone Density	3-4 months after Dental implant placement	Evaluation of bone density around the placed implants using x-ray (CBCT) software analysis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026