Wound Heal
Conditions
Brief summary
This study aims to evaluate the effect of hyaluronic acid and honey compared to saline in healing of multiple extraction sockets of primary teeth in a group of children aging from Two to Seven years old.
Detailed description
A dental extraction is one of the most unpleasant experiences in children, especially for those who have undergone traumatic experiences, and this is likely to reduce future visits to the dental clinic if the treatment is not managed properly. Alveolar osteitis is one of the most common complications following dental extraction. It is considered one of the most studied complications in dentistry, and many risk factors contribute to its occurrence including being a female, young age, tobacco use, difficult or traumatic extractions, pre-existing infection, and use of vasoconstrictor in local anesthesia. Alveolar osteitis occurs during the first three days following the day of extraction, so that the socket is devoid of the blood clot, resulting in the exposure of the bare alveolar bone. Many medicines were and are still used in treating wounds, but they are somewhat expensive.
Interventions
DRUGHyaluronic acid
Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process. use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
DIETARY_SUPPLEMENThoney
Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process. Use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Neither the operator nor the patients could be blinded due to the nature of the study, but the statistician will be blinded.
Intervention model description
Randomized Clinical Trial
Eligibility
Sex/Gender
ALL
Age
2 Years to 7 Years
Healthy volunteers
Yes
Inclusion criteria
* • Age: from Two to Seven years old age. * Both genders. * Children with badly decayed multiple primary teeth beyond repair. * Treated under general anesthesia.
Exclusion criteria
* • History of systemic disease. * Allergy to honey. * Repeatedly used honey during the previous 6 month period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Wound healing size in length and width | After one week will be calculated the size (lentgh and width) of socket | There is only one outcome (wound healing) • Multiple measurements (Digital caliper, color, palpation, presence of pus, gingival margin status). 1. Digital caliper: a device used to calculate the size of the socket (width and length) buccolingual in mesiodistal with measurement of mm. 2. Color: normal (pinkish gingiva) Up normal (reddish gingiva) 3. Palpation: if there is bleeding or not. 4. Presence of pus: yes or no 5. Gingival margin: epithelization (yes or no) |
Contacts
Primary ContactAnas M.gassan Raima, master's
Backup ContactSherine Badr Youness, Associate Prof
Outcome results
None listed