COVID-19
Conditions
Keywords
ECMO
Brief summary
Retrospective single center analyses of COVID-19 patients admitted to the ICU between 01/02/2020 and 31/07/2021.
Detailed description
All adults (\>18 years) with acute hypoxaemic respiratory failure due to diagnosed COVID-19 pneumonia and admitted to ICU from 01/02/2020 until 31/07/2021 were included in the study. Following the World Health Organisation (WHO) protocol 19, laboratory confirmation of COVID-19 infection was defined as a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage. Only laboratory-confirmed patients were included in the analysis. Additional data collection Additional collected parameters are listed below and are collected as a standard-of-care in our hospital: * Demographics: i.e age, gender, BMI * DNR code * Comorbidities: smoking, obesity, hypertension, diabetes, cardiovascular disease, respiratory disease, malignancies, renal failure (AKI), liver failure, gastrointestinal disease, neurological conditions, mental state, other * Symptoms at the time of admission to ICU: i.e fever, body temperature, dyspnoea, headache, diarrhea etc… * Laboratory results of all standard parameters measured * Treatment: antiviral agents, antibiotics, etc… * Complications: shock, heart failure, sepsis, stroke, etc… * Ventilation: method, PEEP, FiO2, P/F ratio ..
Interventions
PROCEDUREECMO
Patients undergoing extracorporeal membrane oxygenation
Sponsors
Jessa Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All adult COVID-19 patients (\>18 years) admitted to the ICU between 01/02/2020 and 31/07/2021 with a laboratory confirmation of COVID-19 infection with a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage
Exclusion criteria
* All adult patients admitted for other reasons to the ICU (no COVID-19 pneumonia)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | through study completion, an average of 1 year | mortality of patients during their stay at the ICU |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 3 Months Mortality | 3 months after admission to ICU | Mortality of patients |
| acute kidney injury | through study completion, an average of 1 year | incidence of acute kidney injury |
| Length of stay in hospital | through study completion, an average of 1 year | Length of stay in hospital |
| Length of stay in ICU | during ICU stay | Length of stay in ICU |
| continous renal replacement therapy | through study completion, an average of 1 year | incidence of continous renal replacement therapy |
Other
| Measure | Time frame | Description |
|---|---|---|
| Complications | through study completion, an average of 1 year | description of possible complications after ECMO |
Countries
Belgium
Outcome results
None listed