Longitudinal Study of a Bionic Eye

Conditions

Choroideremia, Retinitis Pigmentosa

Brief summary

This is a longitudinal observational study with participants who have been implanted with the suprachoroidal retinal prosthesis.

Detailed description

To observe and assess visual, orientation and mobility behavior with primary and adjunct vision processing (AVP) methods that may enhance the performance with the suprachoroidal retinal prosthesis (ScRP). To investigate the effectiveness of primary and AVP methods in the laboratory and real-world environments with the ScRP. Assess structural and functional ScRP stability with objective and subjective assessments. Record participant experiences and feedback with the ScRP.

Lombardi L, Petoe MA, Moussallem L, Kolic M, Baglin EK, Stefopoulos S, Battiwalla X, Walker JG, Barnes N, Abbott CJ, Allen PJ, Bionics Institute and Centre for Eye Research Australia Retinal Prosthesis Consortium.

2025-05-011 citations

10.1167/tvst.14.5.11

Navigational outcomes with a depth-based vision processing algorithm in a second-generation suprachoroidal retinal prosthesis

Lauren Moussallem, Lorinna Lombardi, Myra B. McGuinness, Maria Kolic, Elizabeth K. Baglin et al. (14 authors)

Journal of Neural Engineering2025-04-011 citations

10.1088/1741-2552/adc83a

Second‐Generation (44‐Channel) Suprachoroidal Retinal Prosthesis: Surgical Stability and Safety During a 2‐Year Clinical Trial

Penelope J. Allen, Maria Kolic, Elizabeth K. Baglin, Samuel A. Titchener, Jessica Kvansakul et al. (14 authors)

Clinical and Experimental Ophthalmology2025-01-319 citations

10.1111/ceo.14502

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

No

Inclusion criteria

* Willing to provide signed informed consent; * Implanted with a suprachoroidal retinal prosthesis; * Be available for the study visits; * Willing to comply with study assessments; * In good general health and mobile.

Exclusion criteria

* Medical condition that prohibits mobility; * Anything that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study.

Design outcomes

Primary

Measure	Time frame	Description
Effectiveness of vision processing method in the laboratory.	5 years.	Measure effectiveness of of the vision processing method via observational and quantitative data.
Effectiveness of vision processing method in the 'real world' featured environment.	5 years.	Measure the effectiveness of the vision processing method via observational qualitative and quantitative data in participant 'real world' featured environment.

Secondary

Measure	Time frame	Description
Device stability and functionality.	5 years.	Monitor device stability with routine ophthalmic imaging, impedance and threshold testing.
Participant experience.	5 years	Document participant anecdotal experience with the VP method in 'real world' environments.
Participant interview.	5 years	Interview participants to capture participant experience with the ScRP, determine differences in functional outcomes and utilise this information to improve assessment of functional outcomes.

Countries

Australia

Outcome results