Skip to content

Targeting the Sensory Disturbance in Autism Spectrum Disorder

Targeting the Sensory Disturbance in Autism Spectrum Disorder: The Effectiveness of Cognitive-behavior Therapy-based Virtual Reality Exposure Program

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05157477
Enrollment
90
Registered
2021-12-15
Start date
2020-06-17
Completion date
2027-12-31
Last updated
2026-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autistic Disorders Spectrum

Keywords

autism spectrum; sensory disturbance; intervention; virtual reality; cognitive behavior therapy

Brief summary

This study aims to establish a cognitive-behavior therapy (CBT) based virtual exposure (VR) exposure program to train ASD adults coping with everyday sensory scenarios. Through the practice and training, the ASD participants may learn the strategy to deal with the common sensory scenarios and master the anxiety around the exposure. The anticipatory anxiety and the maladaptive behaviors may be decreased along with the process of desensitization, while the functional impairment related to sensory sensitivity can partly be recovered.

Interventions

BEHAVIORALCBT-based VR exporsure program

This project seeks to establish a 8-week CBT-based VR exposure program to tackle sensory problems in ASD according to the theory of exposure and desensitization (both social and non-social scenarios) as well as identifying dysfunctional thought and searching for alternative thinking. In brief, this program aims to build up the core competence of the ASD individuals in facing the sensory environment, including (1) Relaxation skills (2) Ranking the fearful sensory situations (3) Anxiety coping strategy (3) Graded exposure (4) Cognitive appraisal and restructuring: identifying the dysfunctional thought when facing the social situations and figuring out alternative thinking.

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* young adult aged between 18 and 45 years who had a diagnosis of ASD from a licensed mental health or medical professional based on DSM-5; * has sensory and social problems as reported by the participant and the caregiver; * is motivated to participate in the treatment; * is fluent in Chinese; * has a full-scale IQ \> 70 on WAIS-IV; * scored ≧ 26 on the caregiver-reported Autism Spectrum Quotient (AQ), indicating clinical impairment associated with ASD.

Exclusion criteria

* A history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis) or neurological diseases; * visual impairment and/or hearing impairment that would preclude participation in the CBT-based VR exposure program

Design outcomes

Primary

MeasureTime frameDescription
The change of heart rateTwo months, first time in the first week and second time in the last week.The change of heart rate is related to the activation level of sympathetic nervous system, which can describe the change on anxiety level.

Countries

Taiwan

Contacts

CONTACTYi-Ling Chien, Ph.D
chienyiling@gmail.com+886-2-23123456

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 1, 2026