Arterial Stiffness
Conditions
Brief summary
Hypertension is a disease with increasing and serious complications all over the world. In particular, the incidence of hypertension increases with advancing age. Secondary problems that can be caused by hypertension include peripheral vascular diseases, arteriosclerosis, increased risk of heart attack and stroke. It is a measurement of pulse wave velocity (PWV), a non-invasive indicator of arterial stiffness. It is known that sudden hemodynamic changes that occur during the induction of anesthesia cause undesirable intraoperative and postoperative complications. It is known that arterial stiffness, which is more common in elderly patients, causes orthostatic hypotension in particular. For this reason, more hemodynamic instability may be seen in the general anesthesia procedure in elderly patients with increased arterial stiffness. In our study, we aimed to investigate whether the hemodynamic changes observed during anesthesia induction in hypertensive elderly patients, whom we think have a high pulse wave velocity, are different from normotensive patients.
Interventions
PROCEDUREMobil-O-Graph PWA
After resting in a quiet room preoperatively, blood pressure was measured on the right arm using an oscillometric method.
Sponsors
Aydin Adnan Menderes University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* According to the American Society of Anesthesiologists (ASA), physical condition I-II, * Elective otolaryngology surgery with endotracheal intubation planned * Patients aged 50 and over
Exclusion criteria
* Hypersensitivity to drugs * Difficult intubation history * Diabetes mellitus receiving insulin therapy * Chronic renal failure or end-stage renal disease * Heart failure (left ventricular ejection fraction ≤30%) * Valve disease (moderate to severe) * Atrial fibrillation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference between hemodynamic values | Basal measurement before induction of anesthesia, then at 1-minute intervals until after endotracheal intubation | The difference between the hemodynamic values measured preoperatively and during anesthesia induction was calculated. In addition, ≥20% decrease in preoperative hemodynamic value and/or systolic blood pressure ≤90 mmHg hypotension, ≥20% increased hypertension |
Countries
Turkey (Türkiye)
Outcome results
None listed