A Prospective Study of Performing MRI Simulation in Treatment Position in Spinal Stereotactic Body Radiation Therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05155423

Enrollment

Registered

2021-12-13

Start date

2018-04-21

Completion date

2026-05-24

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Metastases

Brief summary

To learn the usefulness of performing MRI scans in different positions and learn the best practice for spinal stereotactic body radiation therapy (spinal SBRT) planning and dose delivery.

Detailed description

1\. Objectives 1. Assess the feasibility of performing MRI scans in the treatment position for accurate treatment planning and dose delivery in spinal stereotactic body radiation therapy (spinal SBRT). 2. Characterize the improved accuracy of image fusion between MRI and CT and its dosimetric impact when performing MRI scans in treatment position in spinal SBRT. 3. Assess the ability of MRI simulation to accurately target extended spinal targets beyond the current targeting limitations (\>3 consecutive vertebral body levels) 4. Optimize the workflow of using MRI simulation in treatment planning and dose delivery.

Interventions

OTHERmask for immobilization

mask for immobilization

OTHERElekta BodyFix

Elekta BodyFix

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

3.1. Inclusion Criteria 1. Greater than or equal to 18 years of age 2. Pathologically confirmed diagnosis of cancer, including, but not limited to non-small cell lung cancer, breast, prostate, renal cell, melanoma, gastrointestinal, sarcoma, thyroid, head and neck primary, and carcinoma of unknown primary 3. Signed informed consent 4. Willing to undergo 2 MRI simulations in one or multiple sessions, one with immobilization device, and the other without. 5. Patients undergoing spinal SBRT 3.2.

Exclusion criteria

a. Patient with a relative or absolute contraindication to MRI (such as pacemaker, etc.) b. Patients with significant instrumentation or cement at the site of interest causing artifact c. Inability to tolerate with immobilization device for greater than 30 minutes

Design outcomes

Primary

Measure	Time frame
Performing MRI scans in the treatment position for accurate treatment planning.	through study completion, an average of 1 year
Performing MRI scans in the treatment position for dose delivery in spinal stereotactic body radiation therapy (spinal SBRT).	through study completion, an average of 1 year

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORAmol Ghia, MD

M.D. Anderson Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 19, 2026