Abnormal Uterine Bleeding
Conditions
Brief summary
1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination 2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma
Detailed description
The aim of the present study is: 1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination 2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma
Interventions
Norethisterone acetate for 5 months
Sponsors
Assiut University
Ahmed Ali Mahmoud
Study design
Observational model
CASE_ONLY
Time perspective
OTHER
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
Yes
Inclusion criteria
\- (1) age≥30 years; (4) dysmenorrhea, adenomyosis-associated chronic pain, and/or menorrhagia. (3) regular menstrual cycles before administration of norethisterone; (4) no other treatment for adenomyosis/leiomyomatosis at least for 3 months biopsies and histopathology for operated patients;
Exclusion criteria
* (1) pregnant and/or breast-feeding women (2) patients with a ovarian neoplasm, benign ovarian cyst including endometrioma, pelvic inflammatory disease or other endocrine diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| is to evaluate sensitivity and specificity of hysteroscopy in differentiating between uterine adenomyosis and leiomyomatosis | 6 months | Symptomatic improvement |
Countries
Egypt
Contacts
Primary Contactahmed Al Dr, Msc
Backup ContactAhmed Ali
Outcome results
None listed